ROMA-Women is an offshoot of the original ROMA CABG trial designed to address the lack of women in surgical studies, and therefore the lack of guideline-directed surgical care for women patients. Women make up less than one third of participants in cardiac trials, yet they make up roughly half of annual cardiac deaths in the US annually.
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Coronary Disease - Surgery
Ten-Year Outcomes of Off-Pump vs On-Pump Coronary Artery Bypass Grafting in the Department of Veterans Affairs
April 14, 2022
This 10-year follow-up of the ROBY study reports on the primary end points of all-cause death and the composite of death or revascularization among 2203 patients randomized to off-pump or on-pump CABG 2002-2007. Death rates at 10 years were 34.2% for off-pump and 31.1% for on-pump. The composite end point was reached at 4.6 years for off-pump and 5
Registry for Acute Coronary Events in Nigeria (RACE-Nigeria): Clinical Characterization, Management, and Outcome
December 25, 2021
The rising burden of CAD in low- and middle-income countries like Nigeria is a result of the epidemiological transition from communicable to non- communicable diseases. The system of care for acute coronary syndrome (ACS) is evolving and constrained by a lack of prehospital emergency services, prolonged intervention times, and low patient eligibility
2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
December 10, 2021
On December 9, the American Heart Association (AHA) and American College of Cardiology (ACC) jointly released a clinical practice guideline for coronary artery revascularization in patients with coronary artery disease. The top ten take-home messages are:
Minimally invasive coronary bypass surgery with bilateral internal thoracic arteries: Early outcomes and angiographic patency
November 15, 2021
Interesting in its candour mini-series of partial arterial revascularisation by left thoracotomy. The perioperative graft failure is delt in some detail.
November 9, 2021
A good-size Terumo-sponsored RCT that is set to impact on decisions to discontinue DAPT early after PCI with absorbable stent, a change that will somehow decrease the surgical risk of bleeding in the event of salvage CABG.
Timing of Coronary Artery Bypass Grafting After Acute Myocardial Infarction May Not Influence Mortality and Readmissions
June 15, 2021
Fascinating confirmation of null hypotheses including bleeding complications and survival in a Pennsylvanian cohort study, despite the easily predictable previous PCI, hock, and IABP prevalence in the emergency group. The statistical model is elaborate and complex. Perhaps a randomized trial could now be justified!
May 27, 2021
This month's update on the economical and general aspects of the ROOBY-FS trial. The conclusion (on no impact of de novo post-CABG AF on the incidence of stroke nor the 5 year expenditure ) challenges many hitherto perceptions on this frequent compication of coronary surgery.
Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery: A Meta-Analysis
October 26, 2020
Within the limitations of a meta-analysis, a useful work advancing that PCI may have a hitherto masked or hidden mortality
Implications of Alternative Definitions of Peri-Procedural Myocardial Infarction After Coronary Revascularization
October 12, 2020
An analysis, from the cardiology viewpoint, of the MI nomenclature issues around the external validity of the EXCEL trial that undermined the EACTS support of the relevant 2018 guidelines