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Esophageal Cancer - Staging

July 17, 2018
Barbetta and colleagues retrospectively reviewed outcomes for 80 patients with T2N0 esophageal adenocarcinoma, staged by endoscopic ultrasound (EUS) and treated by surgery alone. EUS staging was inaccurate in the majority of patients, and final pathologic staging found nodal disease in 35% of patients.
October 15, 2016
The authors explored the relationship of nodal region and survival from adenocarcinoma of the esophagus/GEJ in patients undergoing induction therapy and transthoracic resection.
November 15, 2015
The goal of this study was to detemine whether adjuvant chemotherapy leads to a survival benefit in patients with positive LNs who have undergone induction chemoradiation therapy followed by esophagectomy. This is a retrospective study of 764 patients undergoing esophagectomy at a single institution from 2000-2013.
September 16, 2015
The 6th and 7th versions of the AJCC staging system were compared for their prognostic accuracy for patients with esophagogastric adenocarcinomas using an institutional database.  The 7th edition system was significantly more accurate in groups undergoing MIE, induction therapy, and overall.
July 17, 2015
Retrospective study of 917 patients undergoing esophagectomy for squamous cell carcinoma at a single hospital in China. In the 7th version of the AJCC staging system for esophageal cancer, nodal stage (N stage) is based solely on the number of lymph node (LN) metastases.
May 17, 2015
In this population-based cohort study with 1044 patients who underwent esophagectomy for esophageal cancer between 1987 and 2010 in Sweden, the researchers found that a higher number of lymph nodes removed did not affect mortality in any specific stage.
September 25, 2014
This retrospective review evaluated the relationship of pretreatment vs post-induction therapy stage to survival in patients undergoing surgery for esophageal adenocarcinoma in 2 centers in London.  Among 584 pts, 400 underwent induction therapy.  Downstaging predicted improved survival (HR 0.43).  Downstaging was associated with decreased rates of l
July 28, 2014
The authors queried whether PET has utility in clinically staging Tis or T1 esophageal cancers; this was a single institution retrospective study involving 79 pts.  The incidence of FDG uptake increased with increasing T status, as did the SUV.  Nodal staging was false positive in 3 pts and false negative all 13 pts with nodal involvement.  Metastati