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Prognostic Significance of the Location of Lymph Node Metastases in Patients With Adenocarcinoma of the Distal Esophagus or Gastroesophageal Junction

Saturday, October 15, 2016

Submitted by

Mark Ferguson

Source

Source Name: Annals of Surgery

Source URL: http://journals.lww.com/annalsofsurgery/Abstract/2016/11000/Prognostic_Significa…

Author(s)

Anderegg, Maarten C. J.; Lagarde, Sjoerd M.; Jagadesham, Vamshi P.; Gisbertz, Suzanne S.; Immanuel, Arul; Meijer, Sybren L.; Hulshof, Maarten C. C. M.; Bergman, Jacques J. G. H. M.; van Laarhoven, Hanneke W. M.; Griffin, S. Michael; van Berge Henegouwen, Mark I.

The authors explored the relationship of nodal region and survival from adenocarcinoma of the esophagus/GEJ in patients undergoing induction therapy and transthoracic resection. Survival diminished related to nodal status/region: highest for no nodes, followed in order by: local/regional, truncal, upper thoracic, and combined truncal and upper thoracic. They suggest that nodal location should be considered in future staging systems.