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Prognostic Significance of the Location of Lymph Node Metastases in Patients With Adenocarcinoma of the Distal Esophagus or Gastroesophageal Junction

Saturday, October 15, 2016

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Anderegg, Maarten C. J.; Lagarde, Sjoerd M.; Jagadesham, Vamshi P.; Gisbertz, Suzanne S.; Immanuel, Arul; Meijer, Sybren L.; Hulshof, Maarten C. C. M.; Bergman, Jacques J. G. H. M.; van Laarhoven, Hanneke W. M.; Griffin, S. Michael; van Berge Henegouwen, Mark I.

The authors explored the relationship of nodal region and survival from adenocarcinoma of the esophagus/GEJ in patients undergoing induction therapy and transthoracic resection.  Survival diminished related to nodal status/region:  highest for no nodes, followed in order by: local/regional, truncal, upper thoracic, and combined truncal and upper thoracic.  They suggest that nodal location should be considered in future staging systems.

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