Death from cardiovascular causes, stroke, or hospitalization with worsening of heart failure or acute coronary syndrome was reduced (P=0.005) by early pharmacogical or inteventional ablation for fast response-atrial fibrillation in a small German RCT
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Dual Antiplatelet Therapy After Percutaneous Coronary Intervention and Drug-Eluting Stents: A Systematic Review and Network Meta-Analysis
September 15, 2020
An open-access large metanalysis on the utility and risks of antiplatelets after PCI. Of note, mortality was not a primary endpoint. The message is that long dual antiplatelet use is an exchange between avoidance of myocardial events and serious bleeding. The novel oral anticoagulants may enter the arena soon..
August 18, 2020
A review that may affect pharma strategy in the immediate future.
A New Role for the Aldosterone/Mineralocorticoid Receptor Pathway in the Development of Mitral Valve Prolapse
May 11, 2020
Interesting hypothesis in a rodent model of myxomatous degeneration.
March 1, 2020
A very easy-to-read editorial that digests a manuscript on the IMPROVE study.
Eating Chocolate to Improve Muscle Health and Walking Ability in Patients With Peripheral Artery Disease
February 20, 2020
The authors revisit the older, somewhat misinterpreted hypothesis of cocoa and vasodilation. The title may again be misinterpreted by the general media as an encouragement to gorge on HIGH CALORIE, HIGH FAT nutrients
November 22, 2019
Puzzling subgroup from the GALILEO trial, which appears in the same issue of the periodical as an article that discredits the use of rivaroxaban as thromboprevention strategy :
November 18, 2019
An editorial related to a recent randomized controlled trial suggesting a striking benefit of anti-inflammatory secondary prevention after recent myocardial events.
New Antihyperglycemic Medications With Cardiovascular Protection for Patients With Diabetes: What do Surgeons Need to Know?
November 11, 2019
A useful narrative on pharmacology and metabolomics for surgeons caring for the diabetic population; the vast majority of the CTSNet membership.
Therapy for Pulmonary Arterial Hypertension in Adults: Update of the CHEST Guideline and Expert Panel Report
September 5, 2019
The January update of an expert panel from the American College of Chest Physicians on the expanding clinical entity of pulmonary hypertension, especially pertinent to the transplant community.