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Pharmacology

November 9, 2021
A good-size Terumo-sponsored RCT that is set to impact on decisions to discontinue DAPT early after PCI with absorbable stent, a change that will somehow decrease the surgical risk of bleeding in the event of salvage CABG. 
November 1, 2021
An extremely useful and free-access update on a major vascular entity. The 'Areas of Uncertainty'  is a particularly useful chapter, discussing the available technology and its current supra-renal limitations and the emerging solutions.
October 21, 2021
A large randomised double-blinded trial reporting a considerable benefit ( 0.79 HR with very small p and supporting confidence intervals) of the Boehringer SGLPT-2 inhibitor regardless of presence of formal diagnosis of diabetes.
September 24, 2021
A comprehensive update on the evidence on the management of acute aortic syndromes, including IMH. Of particular interest is the robust recommendation to bypass non-dedicated aortic centers even to the expense of increased transit time in order to offer management in a Comprehensive Aortic Center (CAC).
September 13, 2021
A brief but dense editorial included in a compedium on cardioplegia. The last sentence summarises what many colleagues would think on the matter of single-shot plegia for root surgery.    
February 21, 2021
An editorial that may herald the decrease in aspirinization and the rise of ticagrelor monotherapy in Percutaneous stenting of coronary arteries.
January 30, 2021
A Canadian multi-centre RCT of immediate baloon-cryoablation of the pulmonary veins: the intervention was compared to the relevant standard of pharmacological care. The target population was treatment-naive sufferers of de novo paroxysmal atrial fibrillation.
January 16, 2021
A recent European consensus paper. Relatively easily read, and favouring meta-analyses over randomised trials. The bulk of the manuscript is of interest to all healthcare providers. The chapters 2.8.1 and 3.1.2 are of additional relevance to the ctsnet readership, as they summarise guidance on interventions.
November 28, 2020
A large RCT with results somewhat supportive of considering a NOAC in the place of warfarin for post operative surgical patients. The study will be weighed against healthcare economical aspects.
November 21, 2020
A scholarly and sober narrative review on , as the authors state,  a ' hot topic' that is already being debated in Multidisciplinary Meetings and Lung Cnacer Boards.

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