The authors queried the UNOS heart transplantation database to determine if LVAD device-related complications (DRCs) were associated with worse postoperative graft survival. The 5 categories of DRCs were as follows: device thrombosis, infection, device malfunction, life-threatening arrhythmias, and others.
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September 19, 2017
Changes in End-Organ Function in Patients With Prolonged Continuous-Flow Left Ventricular Assist Device Support
March 5, 2017
Changes in end organ function were assessed in 59 pts having a continuous flow LVAD in place for more than 3 years. Renal and hepatic function improved initially, but renal function deteriorated to preoperative levels during the follow-up period.
Does Small Size Matter With Continuous Flow Devices? : Analysis of the INTERMACS Database of Adults With BSA ≤1.5 m2
February 15, 2017
The authors reviewed the retrospective INTERMACS database to assess whether outcomes after continuous-flow (CF) LVAD implantation varied with patient BSA. A total of over 10,000 CF LVAD patients were included. Of these, 231 (2%) had a BSA < 1.5 m².
Temporary Mechanical Circulatory Support in Cardiac Critical Care: A State of the Art Review and Algorithm for Device Selection
January 31, 2017
The authors of this review article offer an approach to the utilization of a contempory mechanical circulatory support devices. They further provide insights of the key role that well-functioning interdisciplinary teams contribute to the success of a MCS program and future directions to consider as this field continues to rapidly evolve.
January 27, 2017
Rajamiyer Venkateswaran of Mythenshawe Hospital, Manchester, UK, discusses temporary mechanical circulatory support as a bridge to transplantation in cases of cardiogenic shock.
Cost-Effectiveness of Left Ventricular Assist Devices in Ambulatory Patients With Advanced Heart Failure
January 13, 2017
With the everpresent question of potentially extending LVAD therapy to ambulatory patients with advanced heart failure, the authors--using a Markov model--projected the incremental cost-efffectiveness ratio (ICER) of DT LVADs in this population as compared to conventional medical therapy.
Mechanical circulatory support is associated with loss of platelet receptors glycoprotein Ibα and glycoprotein VI
September 19, 2016
It’s well known that VAD and ECMO are associated with bleeding and decreased platelet activity. This study investigated whether loss of platelet receptors occurred in 21 VAD patients and 20 ECMO patients.
July 5, 2016
With the rapid expansion of mechanical circulatory support (MCS) in various contexts (CVICU, in-hospital cardiac arrest (E-CPR) and the ED), the authors have provided a very nice overview of the general principles of MCS options and management to assist the broader healthcare team involved with these complex patients.
Effects of Additional Intra-aortic Balloon Counter-Pulsation Therapy to Cardiogenic Shock Patients Supported by Extra-corporeal Membranous Oxygenation.
April 8, 2016
ECMO is widely used for cardiogenic shock treatment. Since peripheral V-A ECMO will increase LV afterload and IABP therapy can counterbalance it, will IABP combined with ECMO improve the outcomes?
March 27, 2016
Norepinephrine is often used to maintain the mean pressure during open heart surgery but it is said that it could constrict cerebral arteries, reducing cerebral blood flow. Is it true? The authors explored the association of Norepi doses and rSO2 measured using near-infrared spectroscopy.