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VAD

June 20, 2015
The University of Wisconsin group analyzed the etiology, costs, and effect on survival of unplanned readmissions after LVAD surgery.  At a median follow-up of 11 months, 68 of the 103 patients (66%) were readmitted.  The top 3 causes of readmission were GI bleeding, driveline infection, and stroke.
May 10, 2015
This is a follow up study by the investigators on aortic valve opening during continuous flow LVAD support. Their earlier study looked at the rate of aortic insufficiency during CF LVAD support therapy comparing patients who achieved aortic valve opening during rest versus those who did not.
April 19, 2015
The authors retrospectively analyzed the causes of death and their temporal relationship to surgery for close to 500 patients undergoing LVAD implantation at their institutions.
April 9, 2015
This concensus statement reviews the unique physiology, insertion techniques, and clinical indications for use of percutaneous mechanical circulatory support devices.  As the options for management of different etiologies of heart failure in adult and pediatric populations expand, understanding the advantages of specific devices is vital. 
February 2, 2015
This single instutition study evaluated the impact of mechanical support in children awaiting heart transplant, comparing the pre-support era (1995-2005 and the post-support era (2005-2013); the latter era marked the transition to being able to provide support without concern for pt size.  Support increased from 13% to 37%.  Wait list mortality was d
January 25, 2015
This study from the University of Texas Southwestern sought to analyze the effects of mechanical unloading during prolonged LVAD support on mitochondrial mass, DNA damage response (DDR), and cardiomyocyte proliferation.  Ten matched human samples of LV myocardium were analyzed before and after mechanical circulatory support.
January 17, 2015
The authors perform a meta-analysis of the limited studies available on the utility of tricuspid valve surgery in patients with significant TR at the time of LVAD implantation.  No RCTs are available on this issue; however, six observational studies were analyzed by the group.
December 15, 2014
The CardioWest Total Artificial Heart (CW-TAH) is a pneumatically driven pump that completely replaces the patient’s native ventricles orthotopically.
December 13, 2014
This publication by the University of Louisville group provides an excellent comparative analysis of the outcomes after continuous-flow (CF) vs. pulsatile flow (PF) LVADs.  Although the outcomes after CF LVAD implantation are clearly superior than those of PF LVADs, there are certainly unique morbidities after CF LVAD implantation.
December 11, 2014
In this Duke study, all CF LVAD implantations during the 2005 to 2013 era were analyzed, and those patients who underwent CF LVAD implantation and later replacement were reviewed.

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