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Causes and timing of death during long-term follow-up after transcatheter aortic valve replacement.

Monday, February 2, 2015

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Source

Source Name: American Heart Journal

Author(s)

Saia F, Latib A, Ciuca C, Gasparetto V, Napodano M, Sticchi A, Anderlucci L, Marrozzini C, Naganuma T, Alfieri O, Facchin M, Hoxha B, Moretti C, Marzocchi A, Colombo A, Tarantini G.

This manuscript describes the findings of a retrospective analysis of 874 consecutive high risk or inoperable patients undergoing TAVR in three different centres, evaluating outcomes after up to three years of follow up. In-hospital mortality was 5%. Early mortality was strongly associated with the occurrence of procedural complications. The relative incidence of non-cardiovascular death increased with time to become the principal cause of mortality beyond 6 months and outnumbering cardiovascular mortality beyond 24 months. Cumulative mortality at three years was 31.5%. Baseline comorbidities, particularly COPD and renal impairment, had a major detrimental impact on long-term mortality.

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