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CT Screening for Lung Cancer: Nonsolid Nodules in Baseline and Annual Repeat Rounds

Wednesday, June 24, 2015

Submitted by

Mark Ferguson

Source

Source Name: Radiology

Source URL: http://pubs.rsna.org/doi/abs/10.1148/radiol.2015142554

Author(s)

David F. Yankelevitz, Rowena Yip, James P. Smith, Mingzhu Liang, Ying Liu, Dong Ming Xu, Mary M. Salvatore, Andrea S. Wolf, Raja M. Flores, Claudia I. Henschke, As the Writing Committee for The International Early Lung Cancer Action Program Investigators Group

The ELCAP data set was evaluated for pts identified with non-solid nodules at baseline or during follow-up. 2392 (4.2%) pts had nonsolid nodules at baseline, of which 73 were diagnosed as adenocarcinoma. A new nodule was identified in an additional 485 (0.7%) pts, of whom 11 were diagnosed with adenocarcinoma. Nonsolid nodules improved in 66% of pts. Median time to cancer treatment was 19 mos, and survival was 100% at a median follow-up of 78 mos. 22 of these pts had a solid component develop during f/u and prior to therapy. The group recommends that nonsolid nodules can be safely followed with CT at intervals of 12 months.