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Lung

Therapy for Pulmonary Arterial Hypertension in Adults: Update of the CHEST Guideline and Expert Panel Report

The January update of an expert panel from the American College of Chest Physicians on the expanding clinical entity of pulmonary hypertension, especially pertinent to the transplant community.

Preoperative Serum Lactate Dehydrogenase Level as a Predictor of Major Complications Following Thoracoscopic Lobectomy: A Propensity-Adjusted Analysis

Zhang and colleagues examined serum biomarker levels in patients undergoing a lobectomy using video-assisted thoracic surgery. Among 626 patients, they found that preoperative serum LDH was an independent predictor of 90-day cardiopulmonary complications. The authors recommend including LDH measurements in the risk assessment process prior to major lung resection.

BMI, BMI Change, and Overall Survival in Patients With Lung Cancer

This study of over 25,000 pts from the International Lung Cancer Consortium identified underweight and severly obese patients as having poorer survival than others, whereas a survival advantage was evident among patients who were overweight or mildly obese.  Decreased BMI (wt loss) was associated with poorer outcomes across all BMI categories.

Novel Machine Learning Approach to Identify Preoperative Risk Factors Associated With Super-Utilization of Medicare Expenditure Following Surgery

Using a machine learning algorithm, resource utilization among more than 1 million Medicare patients undergoing one of 6 operations including CABG and lung resection was analyzed.  Super users comprised 4.8% of the cohort but consumed 31.7% of the resources.  Risk factors for super use included paraplegia/hemiplegia, weight loss, and CHF combined with chronic kidney disease. 

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