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Detection of Lung Cancer and EGFR Mutation by Electronic Nose System

Monday, October 2, 2017

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Source Name: Journal of Thoracic Oncology


Dekel Shlomi, Manal Abud, Ori Liran, Jair Bar, Naomi Gai-Mor, Maya Ilouze, Amir Onn, Alon Ben-Nun, Hossam Haick, Nir Peled

Researchers used  a nanomaterial sensor array and pattern recognition statistical techniques to evaluate exhaled breath samples from patients with suspicious lesions on imaging.  A total of  119 patients were included, of whom 30 had benign lesions.  In cancer patients, the accuracy of discriminating EGFR mutations from wild-type EGFR was 83%.  The accuracy of differentiating early stage cancer from benign disease was 87%.

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