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Ex Vivo Heart Perfusion Offsets Ischemic Penalties With ≥6-Hour Preservation in Adult Donation-After-Brain-Death Heart Transplantation

Submitted by: Mujtaba MubashirGold Contributor

Source: The Journal of Thoracic and Cardiovascular Surgery

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Author(s): Alexander R. Berg, Aravind Krishnan, Elbert E. Heng, Ashley Y. Choi, Alice Zhou, Daniel I. Alnasir, Y. Chawannuch Ruaengsri, Yasuhiro Shudo, Y. Joseph Woo, John W. MacArthur

This retrospective analysis of the UNOS registry investigated patients after the latest allocation revision and examined whether ex vivo heart perfusion (EVHP) mitigated ischemic penalties in adult donation-after-brain-death heart transplants with preservation times of six hours or more. Among 546 recipients who met the criteria (320 receiving EVHP and 226 undergoing static/hypothermic storage), EVHP was associated with superior one-year survival (92.5 percent vs 86.3 percent, p=0.029) and three-year survival (90.9 percent vs 79.6 percent, p

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