This week on The Beat, CTSNet Editor-in-Chief Joel Dunning spoke with Dr. Christopher McGregor about the current state of cardiac and kidney xenotransplantation.
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Transplant
December 4, 2025
Sir Terence English, the pioneering cardiac surgeon who performed the United Kingdom’s first successful heart transplant in 1979, has died at the age of 93. His groundbreaking work helped Royal Papworth Hospital achieve an international reputation for heart transplantation and, later, heart-lung and lung transplants.
November 25, 2025
This article examines both preclinical and clinical results in cardiac xenotransplantation, highlighting the ongoing challenges in achieving consistent and durable clinical graft survival.
November 13, 2025
This study analyzed 3,394 pediatric congenital heart disease (CHD) patients listed for heart transplant from 2014 to 2023. Of these, 16.5 percent received ventricular assist device (VAD) support while waitlisted. Waitlist mortality was higher in the VAD group (25.7 percent vs 16.2 percent).
November 11, 2025
This video demonstrates a beating heart transplant using the Organ Care System ("Heart-in-a-Box").
November 6, 2025
This study analyzed 32,036 adult heart transplant recipients from 2010 to 2023 to assess long-distance donor (LDD) utilization after the 2018 allocation policy change. LDD use increased from 5.5 percent to 14 percent, with mean donor distance rising from 171 to 288 miles.
October 23, 2025
This retrospective study analyzed 35,038 U.S. lung transplant recipients, of which 526 also received kidney transplants for renal replacement or chronic kidney disease (CKD) stages 3b-5.
October 3, 2025
At the American Society for Artificial Internal Organs (ASAIO) 2025 Annual Conference, Dr. Randall C. Sterling, a Professor Emeritus of Medicine at the Kaufman Center for Heart Failure Treatment and Recovery at the Cleveland Clinic Lerner College of Medicine, delivered a presentation titled “My Personal Journey With MCS: History and Milestones.”
September 25, 2025
This article reports the first pig-to-human lung xenotransplantation, marking a major milestone in thoracic transplantation research. A six-gene-edited porcine lung was transplanted into a 39-year-old brain-dead human recipient and monitored for 216 hours.
September 18, 2025
In this remarkable interview, CTSNet Editor-in-Chief Joel Dunning speaks with Alexis Shafii, professor of surgery and surgical director of heart transplantation at The Texas Heart Institute at Baylor College of Medicine, about the first in-human BiVACOR total artificial heart implantation.