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Left Atrial Appendage Occlusion During Cardiac Surgery to Prevent Stroke

Friday, May 21, 2021

Submitted by

Aristotle Protopapas

Source

Source Name: The New England Journal of Medicine

Source URL: https://www.nejm.org/doi/full/10.1056/NEJMoa2101897

Author(s)

Richard P. Whitlock, Emilie P. Belley-Cote, Domenico Paparella, Jeff S. Healey, Katheryn Brady, Mukul Sharma, Wilko Reents, Petr Budera, Andony J. Baddour, Petr Fila, P.J. Devereaux, Alexander Bogachev-Prokophiev, Andreas Boening, Kevin H.T. Teoh, Georgios I. Tagarakis, Mark S. Slaughter, Alistair G. Royse, Shay McGuinness, Marco Alings, Prakash P. Punjabi, C. David Mazer, Richard J. Folkeringa, Andrea Colli, Álvaro Avezum, Juliet Nakamya, Kumar Balasubramanian, Jessica Vincent, Pierre Voisine, Andre Lamy, Salim Yusuf, Stuart J. Connolly, M.D., et al., for the LAAOS III Investigators

A large RCT concluding that 'surgical occlusion of the left atrial appendage provides additional protection against stroke when added to anticoagulation.' A number of limitations are briefly discussed. Findings are interesting in that absolute absence of surgical complications has been declared.