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Prediction of Response to Anti-PD-1 Therapy in Patients With Non-small-cell Lung Cancer by Electronic Nose Analysis of Exhaled Breath

Friday, September 20, 2019

Submitted by

Mark Ferguson

Source

Source Name: Annals of Oncology

Source URL: https://academic.oup.com/annonc/advance-article/doi/10.1093/annonc/mdz279/556748…

Author(s)

R de Vries, M Muller, V van der Noort, W S M E Theelen, R D Schouten, K Hummelink, S H Muller, M Wolf-Lansdorf, J W F Dagelet, K Monkhorst, A H Maitland-van der Zee, P Baas, P J Sterk, M M van den Heuvel

Immune checkpoint inhibitors have revolutionized treatment of non-small cell lung cancer. In this study, breath prophiles were collected from 143 patients and a single biomarker profile was created that detected responses to anti-PD-1 treatment with 89% accuracy.