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Sex Differences in the Utilization and Outcomes of Surgical Aortic Valve Replacement for Severe Aortic Stenosis
The Nationwide Inpatient Sample (NIS) was queried for aortic valve replacements conducted between 2003 and 2014. The data on a total of 166,809 patients (37% female) were analyzed with respect to outcomes in men vs. women. Hospital mortality was 40% higher in women than men (5.6% v. 4%, p<0.001). When isolated AVRs were analyzed and propensity-matched, hospital mortality was 14% higher in women than men (3.3% v. 2.9%, p=0.001). The differential outcomes appear to be driven by a distinct risk profile.