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Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology

Wednesday, November 12, 2014

Submitted by

Marcelo Jimenez

Source

Source Name: BioMed Central Cancer

Source URL: http://www.biomedcentral.com/1471-2407/14/778

Author(s)

Emily A Vucic, Kelsie L Thu, Larissa A Pikor, Katey SS Enfield, John Yee, John C English, Calum E MacAulay, Stephen Lam, Igor Jurisica and Wan L Lam

This study was conducted in 94 lung adenocarcinoma patients matching pairs from current, former and never smokers' lung adenocarcinoma and non-malignant lung parenchymal tissue. Investigators discovered different smoking-specific microRNA differences. These findings may explain distinct tumorigenic processes influenced by different smoking and non-smoking expositions.