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Spread Through Air Spaces is an Independent Predictor of Recurrence in Stage III (N2) Lung Adenocarcinoma

Wednesday, July 10, 2019

Submitted by

Claire Vernon

Source

Source Name: Interactive Cardiovascular and Thoracic Surgery

Source URL: https://doi.org/10.1093/icvts/ivz116

Author(s)

Yuriko Terada, Tsuyoshi Takahashi, Shigeki Morita, Kosuke Kashiwabara, Kazuhiro Nagayama, Jun-Ichi Nitadori, Masaki Anraku, Masaaki Sato, Aya Shinozaki-Ushiku, Jun Nakajima

Spread through air space (STAS) is a pattern of lung adenocarcinoma invasion, and it is a predictor of recurrence in patients with early-stage lung adenocarcinoma. However, less is known about the role of STAS in advanced lung adenocarcinoma. In this retrospective study including 76 patients with stage III lung adenocarcinoma, the presence of a STAS invasion pattern was a significant risk factor for adenocarcinoma relapse.