This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Is Subvalvular Repair Worthwhile in Severe Ischemic Mitral Regurgitation? (from the Papillary Muscle Approximation trial)

Tuesday, September 27, 2016

Submitted by


Francesco Nappi, MD, Cristiano Spadaccio, MD, PhD∗, Antonio Nenna, MD, Mario Lusini, MD, PhD, Massimiliano Fraldi, PhD, Christophe Acar, MD, Massimo Chello, MD

The authors performed a subgroup analysis of the Papillary Muscle Approximation (PMA) trial, a randomized trial that, while showing superiority of PMA + restrictive annuloplasty (RA) over RA alone in terms of LV remodeling and MR recurrence, failed to show a survival advantage and was plagued by a relatively high incidence of reoperation.  In this study, the authors found that the best outcomes were seen in patients with preop symmetric tethering, asymmetric tethering, or inferior wall dyskinesia.  Patients with primarily anterolateral wall dysfunction did not benefit from the addition of the PMA.

Add comment

Log in or register to post comments