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Survival and Recurrence of Endocarditis Following Mechanical Versus Biological Aortic Valve Replacement for Endocarditis in Patients Aged 40 to 65 Years: Data From the INFECT-Registry

Wednesday, March 27, 2024

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Source Name: Journal of Clinical Medicine


Salsano A, Di Mauro M, Labate L, Della Corte A, Lo Presti F, De Bonis M, Trumello C, Rinaldi M, Cura Stura E, Actis Dato G, Punt

Overall, 4,365 patients were diagnosed and operated on for infective endocarditis (IE) from 2000 to 2021. Long-term survival was significantly higher among patients receiving a mechanical prosthesis than those receiving a biological prosthesis (hazard ratio [HR] 0.546, 95 percent CI: 0.322-0.926, p= 0.025). Mechanical prostheses were associated with significantly less recurrent endocarditis after AVR than biological prostheses (HR 0.268, 95 percent CI: 0.077-0.933, p= 0.039). The present analysis of the INFECT-REGISTRY shows increased survival and reduced recurrence of endocarditis after a mechanical aortic valve prosthesis implant for IE in middle-aged patients.

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