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Endocarditis and Inflammatory Diseases

August 28, 2025
In this retrospective study, the authors analyzed outcomes in 245 patients with left-sided infective endocarditis (IE) and noninfected cardiac implantable electronic devices (CIEDs) who underwent cardiac surgery, using data from the CAMPAIGN Registry, which included 4,917 patients operated on between 1994 and 2018.
June 18, 2025
This review article aims to examine the surgical approach to patients with failed mitral transcatheter edge-to-edge repair (M-TEER), focusing on operative challenges, decision-making, and contemporary outcome data. Technical considerations, including device removal and the management of complex mitral valve (MV) anatomy, are discussed.
April 10, 2025
In this study, the authors investigate the clinical presentation, microbiological profile, and outcomes of infective endocarditis in octogenarians. This multicenter retrospective analysis, utilizing data from the CAMPAIGN Registry, includes 4,917 consecutive patients suffering from infective endocarditis.
February 27, 2025
This study analyzed mechanisms of repair failure after mitral valve repair using chordal replacement and annuloplasty for degenerative mitral regurgitation. Between 2003 and 2010, 344 patients underwent mitral valve repair at the German Heart Center Munich.
February 13, 2025
Infective endocarditis (IE) remains one of the most challenging diseases of modern times. It is associated with high mortality and morbidity despite significant improvements in diagnostic and surgical skills, and antibiotic pretreatment.  
July 8, 2024
This video shows the case of a patient with aortic root endocarditis with abscesses treated with a homograft.
May 2, 2024
Some patients with infective endocarditis receive exclusively conservative antibiotic treatment due to their comorbidities and high operative risk, despite fulfilling criteria for surgical therapy.
April 2, 2024
The well-known cone procedure with detachment, displacement, and rotation of the leaflet has been designed for patients with Ebstein anomaly. However, the authors think that it may be used for any situation in which the septal and/or posterior leaflets are defective or non-functional. This video shows how the cone repair can be used successfully in an endocarditis patient where the septal cusp is completely destroyed.
March 27, 2024
Overall, 4,365 patients were diagnosed and operated on for infective endocarditis (IE) from 2000 to 2021. Long-term survival was significantly higher among patients receiving a mechanical prosthesis than those receiving a biological prosthesis (hazard ratio [HR] 0.546, 95 percent CI: 0.322-0.926, p= 0.025).
December 20, 2023
In this LACES “Experts’ Insights” interview, Dr. Michael Borger, co-chair of the recently published 2023 ESC/EACTS Endocarditis Guidelines, briefly summarizes the most important take-home messages and changes of the guidelines.

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