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Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Surgical Valves

Tuesday, July 8, 2014

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Source Name: Journal of the American Medical Association


Danny Dvir; John G. Webb; Sabine Bleiziffer; Miralem Pasic; Ron Waksman; Susheel Kodali; Marco Barbanti; Azeem Latib; Ulrich Schaefer; Josep Rodés-Cabau; Hendrik Treede; Nicolo Piazza; David Hildick-Smith; Dominique Himbert; Thomas Walther; Christian Hengstenberg; Henrik Nissen; Raffi Bekeredjian; Patrizia Presbitero;Enrico Ferrari; Amit Segev; Arend de Weger; Stephan Windecker; Neil E. Moat; Massimo Napodano; Manuel Wilbring;Alfredo G. Cerillo; Stephen Brecker; Didier Tchetche; Thierry Lefèvre; Federico De Marco, MD; Claudia Fiorina, MD;Anna Sonia Petronio; Rui C. Teles; Luca Testa; Jean-Claude Laborde; Martin B. Leon; Ran Kornowski

The consortium of authors of this paper determined the survival after Transcatheter valve in valve implantation inside a failed surgical bioprosthesis. The authors report a 1 month mortality rate of 7.6% and a major stroke rate of 1.7%. One-year survival was 83.2%, and 313 (92.6%) of survivors had a good functional status (NYHA I/II). Patients who had an aortic stenosis (n=181) had worse 1-year survival (76.6%) than patients with aortic regurgitation (91.2%) or combined stenosis/regurgigation (83.9%; p=0.01). Moreover, a small surgical bioprosthesis was associated with higher mortality. 

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