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Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve Disease

Sunday, December 7, 2014

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Source

Source Name: Journal of the American College of Cardiology

Author(s)

Mylotte D, Lefevre T, Søndergaard L, Watanabe Y, Modine T, Dvir D, Bosmans J, Tchetche D, Kornowski R, Sinning JM, Thériault-Lauzier P, O'Sullivan CJ, Barbanti M, Debry N, Buithieu J, Codner P, Dorfmeister M, Martucci G, Nickenig G, Wenaweser P, Tamburino C, Grube E, Webb JG, Windecker S, Lange R, Piazza N.

In this retrospective, multicentre study, the authors evaluate clinical outcomes in 139 patients with bicuspid aortic valves undergoing transcatheter aortic valve implantation (TAVI) with either a self or a balloon-expandable prosthesis. Short and intermediate clinical outcomes were encouraging, demonstrating the feasibility of TAVI in this group of patients. The mean finding was a high prevalence (28.4%) of post procedural more than  grade II aortic regurgitation (AR). Nevertheless, when the measures for sizing had been obtained with multislice computed tomography, more than grade II AR was detected in 17.4% of the patients. No significant differences were found between self and balloon-expandable prosthesis.

Comments

28.4% of grade II AR in patients with mean STS score of 4.9%? I wouldn't call these results encouraging!
one in four develops more than grade 2 aortic regugitation...poor results

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