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Transcatheter Versus Surgical Aortic Valve Replacement: Propensity-Matched Comparison
In this large propensity-matched study, outcomes after Transcatheter versus Surgical Aortic Valve Replacement (TAVR vs. SAVR) were assessed in a real world intermediate- and high-risk cohort of 9500 patients in the United States. There was no difference in 1-year mortality (17.3% vs. 17.9%; HR 0.93, 95% confidence interval [CI] 0.83-1.04) and stroke (4.2% vs.3.3% HR 1.18; 95% CI 0.95-1.47). Results were consistent among subgroups of patients. Importantly, there were no differences in effect across the male/female subgroups. This shows that not gender in itself, but rather gender-related comorbidities play a role in a better outcome of TAVR in female patients. This important study shows data from daily practice and further confirms the results of randomized controlled trials.