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World's First Randomized Study of Mini-Sternotomy AVR Versus Conventional AVR: 271 Patients and the Results Might Surprise You
I believe that this is the world's first randomized controlled trial of mini aortic valve replacement (AVR) versus full sternotomy AVR.
It is a very well-conducted study where the surgeon was randomly assigned to perform an AVR by sterntomy or by manubrium-only. The same consultant surgeon performed either operation after randomization. No trainee performed any operations as operating surgeon. The protocol was very tightly adhered to.
The primary outcome was red cell transfusion at 7 days, and there were many secondary outcomes including length of stay, complications, etc, as might be expected.
The mean age was 69 and the mean EuroSCORE was 5.2 and the groups were perfectly matched.
The bypass time was 82 minutes in the ministernotomy group and 59 minutes in the sternotomy group.
The major outcome results might surprise you! Click on the link to find out!