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Journal and News Scan

Source: News from around the web.
Author(s): Claire Vernon

Patient Care

US states that implemented policies for screening newborns for critical congenital heart disease have seen reductions in infant cardiac deaths compared to states that didn’t implement screening.

Jimmy Kimmel’s infant son, whose medical care has been in the spotlight as part of the US healthcare debate, is recovering from his second heart surgery.

The man who received the first locally-developed mechanical heart valve in India, the TTK-Chitra valve, celebrates 27 years with his mechanical valve.

Surgeons in New York City remove a tennis ball-sized tumor from a man’s heart.

 

Drugs and Devices

The US Food and Drug Administration announced new guidance on 3D-printed medical devices.

A transcatheter device for mitral regurgitation that is anchored entirely in the left atrium was awarded Best Technology Parade Presentation at the International Conference for Innovations in Cardiovascular Interventions in Tel Aviv, Israel.

Edwards Lifesciences has purchased Harpoon Medical, including its mitral valve repair device that is expected to receive CE mark approval soon.

 

Research, Trials, and Funding

Adding atezolizumab, an anti-PD-L1 immunotherapy, to an antiangiogenic biologic drug and chemotherapy delayed progression of non-small cell lung cancer regardless of PD-L1 expression, in an early report from the phase III IMpower150 trial.

Former US National Football League athletes were found to have a higher incidence of an ascending aorta over 4 cm wide than similarly aged men who were not professional athletes.

Apple and Stanford University have launched the Apple Heart Study, which uses an app linked to the Apple Watch to monitor participants for irregular heart rhythms.

Source: The Annals of Thoracic Surgery
Author(s): Alexander Iribarne, Philip P. Goodney, Alyssa M. Flores, Joseph DeSimone, Anthony W. DiScipio, Andrea Austin, Jock N. McCullough

Iribarne and colleagues analyzed US Medicare claims from 2009 to 2014 to characterize bilateral internal mammary artery (BIMA) usage in coronary artery bypass surgery. They found that regional usage of BIMA differed significantly, and that BIMA usage was related to the intensity of cardiovascular care but only somewhat to surgical volume.

Source: World Journal for Pediatric and Congenital Heart Surgery
Author(s): John M. Costello, Elizabeth Preze, Nguyenvu Nguyen, Mary E. McBride, James W. Collins, Osama M. Eltayeb, Michael C. Mongé, Barbara J. Deal, Michelle M. Stephenson, Carl L. Backer

This study encompasses 2,363 pediatric patients who underwent cardiac surgery before and after the implementation of an acuity adaptable care model. Under the conventional model, patients moved among units and care teams based on age, operative status, and acuity. Under the acuity adaptable care model, patients remained in the Cardiac Care Unit and received care from one clinical team throughout their hospitalization. The acuity adaptable care model was associated with a lower failure-to-rescue rate and favorable trends for operative mortality and length of stay.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Antonella LoMauro, Andrea Aliverti, Melania Chiesa, Margherita Cattaneo, Emilia Privitera, Davide Tosi, Mario Nosotti, Luigi Santambrogio, Alessandro Palleschi

LoMauro and colleagues measured tidal volume and ribcage expansion during rest and exercise to evaluate functional recovery after minimally invasive thoracic surgery. Video-assisted thoracoscopic surgery (VATS) preserved these kinematic measures better than posterolateral thoracotomy, and the advantage was observed over two postoperative months. Patients compensated for restriction by shifting the expansion to the contralateral thorax after VATS and to the abdomen after thoracotomy.

Source: The Annals of Thoracic Surgery
Author(s): Rohun Bhagat, Michael R. Bronsert, Austin N. Ward, Jeremiah Martin, Elizabeth Juarez-Colunga, Natalia O. Glebova, William G. Henderson, David Fullerton, Michael J. Weyant, John D. Mitchell, Robert A. Meguid

Bhagat and colleagues analyzed the rate of unplanned hospital readmission from 2012 to 2015 using the American College of Surgeons National Surgical Quality Improvement Program Participant Use File. Thoracoscopic surgery was associated with a higher rate of postdischarge complications, a finding related to the shorter length of stay for these patients. Open surgery was associated with a higher rate of related unplanned readmissions, but after risk adjustment, open and thoracoscopic surgery readmissions were not different.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Friedrich-Wilhelm Mohr

An inspiring presidential address from the new EACTS president. 

Source: News from around the web.
Author(s): Claire Vernon

Patient Care

December 3rd is the 50th anniversary of the first human heart transplantation, and the occasion is being commemorated with an event in Cape Town and writing about the historic event.

The president of Brazil had stents placed for coronary artery obstructions over the weekend.

The first transcatheter implantation of a retrievable aortic valve in China occurred at the Second Affiliated Hospital of Zhejiang University.

 

Drugs and Devices

A UK-based company is developing a more mobile, more affordable surgical robot.

Boston Scientific announced that it will indefinitely delay seeking US Food and Drug Administration approval for its Lotus Edge transcatheter valve.

Puerto Rico’s ongoing recovery from Hurricane Maria could affect surgical device supplies.

The European Medicines Agency will move from London to Amsterdam.

 

Research, Trials, and Funding

Researchers from the University of California, San Diego, in the US, find that lobectomy for early stage lung cancer provides better survival than stereotactic body radiation therapy.

A review of randomized controlled trials in pediatric heart surgery suggests that many studies do not provide sufficiently robust evidence.

A new imaging technology could provide higher resolution views of important tissues in minimally invasive surgery.

Biomedical engineers from Duke University in North Carolina, US, have implanted patches of induced cardiomyocytes onto rodent hearts; the implants showed near mature electrical and mechanical function.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Hiroshi Sato, Toshiro Ito, Yosuke Kuroda, Hiroki Uchiyama, Toshitaka Watanabe, Naomi Yasuda, Junji Nakazawa, Ryo Harada, Nobuyoshi Kawaharada

Sato and colleagues applied elliptic Fourier analysis to morphological aortic measurements from 80 patients with uncomplicated type B aortic dissection. The patients were divided in two groups according to aortic enlargement during follow-up. The shape of the aortic diameter at initial operation was a significant predictor of further morphologic development.

Source: New England Journal of Medicine
Author(s): Gregory E. Holt, Bianca Sarmento, Daniel Kett, Kenneth W. Goodman

An interesting dilemma posed by a tattoo providing advanced care directives.

Source: CNN
Author(s): Jacqueline Howard

Newspaper and prime time TV advertisements are beginning in the US today that detail the medical toll that smoking exacts on its victims.  The ads are paid for by big tobacco based on a court order from 2006 that has finally survived the appeal process.  A spokesperson for one of the companies stated that they hope to "develop less risky tobacco products."  The ads emphasize that smoking causes nearly 500,000 deaths annually in the US.

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