ALERT!
This site is not optimized for Internet Explorer 8 (or older).
Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.
Journal and News Scan
In this article, the authors analyzed 6,693 redo coronary artery bypass grafting (CABG) operations performed between 1980 and 2020 at the Cleveland Clinic to determine whether multiarterial grafting (MAG) provides a survival benefit over single arterial grafting (SAG). Using propensity-matched cohorts (2,005 pairs), they found that MAG resulted in lower in-hospital mortality (1.7 percent vs 2.8 percent) and comparable morbidity. Long-term survival was significantly better after MAG, particularly in men receiving bilateral internal thoracic artery (ITA) grafts, with a 20-year survival rate of 31 percent compared to 25 percent after SAG. No clear survival advantage was observed in women or when non-ITA conduits were used. The authors note that CABG is technically more complex in women, whose smaller arteries and limited collateralization may partly explain the limited observed benefit.
The EACTS recently released an expert consensus statement on the Ross procedure in adult patients, highlighting the renewed focus in this area due to increasing evidence of excellent long-term outcomes. These outcomes include restoration of life expectancy and improved valve-related outcomes. The Ross procedure is now considered a viable first-line option for selected young and middle-aged adults with nonrepairable aortic valve disease. Currently, its adoption remains inconsistent across institutions, partly due to concerns about surgical complexity, long-term durability, and the need for structured follow-up. This expert consensus statement discusses the rationale for increasing adoption, surgical technique, patient selection, and standardization procedures in centers of excellence.
In this study, the authors evaluated a novel aortic anastomotic stapler for repairing acute type A aortic dissections using a human cadaver model. Ten felt sandwich repairs were performed, with half completed using conventional sutures and the other half using the stapler. The stapler significantly reduced procedure time (median 2:22 vs 6:40 minutes) without increasing leakage. Importantly, the stapled group showed no distal anastomotic new entry, false lumen perfusion, or dissection progression, while these complications occurred in the sutured group. Microscopy confirmed less tissue trauma with the stapler. The device achieved reliable pin deployment and faster, more homogeneous sealing than sutures. While limited to cadaveric testing, these findings suggest this device may improve safety and efficiency in type A dissection repair, warranting further in vivo validation.
This article presents the first comparative analysis of outcomes after tracheobronchoplasty (TBP) for excessive dynamic airway collapse (EDAC) and tracheobronchomalacia (TBM), two distinct but often conflated causes of excessive central airway collapse (ECAC). In this single-center retrospective study of 73 patients (47 with EDAC and 26 with TBM), the authors used dynamic CT imaging reviewed by airway experts to establish a gold-standard diagnosis. Despite anatomical and pathophysiologic differences, postoperative outcomes were comparable between EDAC and TBM in terms of complication rates, intensive care units (ICU) and hospital stays, readmissions, and quality-of-life improvements. Both groups experienced significant gains in respiratory symptoms and six-minute walk test performance following TBP.
The study highlights that while differentiating EDAC from TBM remains diagnostically challenging, these distinctions do not translate into differences in surgical benefit, supporting TBP as a definitive and effective treatment for severe ECAC regardless of the cause. Importantly, the findings underscore the need for refined diagnostic standards, multidisciplinary evaluation, and expanded surgical candidacy criteria.
For the global cardiothoracic surgery audience, this paper is significant because it clarifies disease mechanisms and outcomes for a rare but increasingly recognized cause of airway obstruction. It informs evolving robotic and open TBP approaches, emphasizes the importance of multidisciplinary collaboration between surgeons and interventional pulmonologists, and sets the stage for multicenter efforts to standardize diagnosis and management of complex airway disorders.
An analysis of 10 trials involving more than 10,000 patients with non-acute heart disease compared outcomes for three treatment strategies: optimal medical therapy (OMT), percutaneous coronary intervention (PCI) with OMT, and coronary artery bypass grafting (CABG) with OMT.
Using a network meta-analysis, scientists found that CABG with OMT was the most effective strategy for reducing long-term mortality, myocardial infarction, and the need for repeat procedures. For example, CABG+OMT had a lower hazard ratio (HR) vs OMT (0.84, 95 percent credible interval (CrI) 0.68−1.07) compared to PCI+OMT vs OMT (0.93, 95 percent CrI 0.79−1.16). The probability of CABG+OMT being the best treatment for mortality was 88.1 percent.
The European Association for Cardio-Thoracic Surgery (EACTS) has developed a unified Core Curriculum for cardiac surgical training to address variations in training standards across Europe. Created with contributions from 26 national programs, the curriculum outlines competencies across three stages of training—introductory, intermediate, and advanced. It emphasizes competency-based progression, minimum case requirements, standardized assessments, and robust quality assurance. While adoption is voluntary, the curriculum is designed to enhance training quality, safeguard patient care, and support surgeon mobility across European borders.
This retrospective study analyzed 35,038 U.S. lung transplant recipients, of which 526 also received kidney transplants for renal replacement or chronic kidney disease (CKD) stages 3b-5. The findings demonstrates that sequential lung–kidney transplantation yielded superior long-term survival compared to simultaneous procedures, particularly in CKD patients. While simultaneous transplants were associated with reduced short-term mortality compared to lung-only transplantation. Overall, kidney transplantation decreased the mortality risk by 40 percent. These results indicate that sequential transplantation enables better postoperative risk management. The 2023 OPTN “safety-net” policy, which prioritizes kidneys for recent lung recipients, is supported by these findings as a means to improve survival in thoracic patients with renal dysfunction.
The authors conducted a randomized study involving 40 patients undergoing off-pump coronary artery bypass grafting (CABG) to compare techniques for preparing internal thoracic arteries. They found that skeletonized grafts showed endothelial disruption, reduced endothelial nitric oxide synthase staining, and lower plasma nitric oxide levels when compared with pedicled grafts without endothoracic fascia. Endothelin-1 release and EDN1 mRNA expression were significantly higher in skeletonized arteries. The authors concluded that skeletonization impairs endothelial integrity and shifts the nitric oxide-endothelin balance, which may negatively affect graft performance.
Artificial intelligence is increasingly being embedded into clinical research workflows, covering aspects from data processing and modeling to manuscript drafting. While the human role remains essential—particularly in hypothesis formulation, clinical interpretation and ethical oversight—it is becoming more supervisory, curatorial, or interpretive. In this context, the term “AI-assisted medical writing” may no longer be appropriate. A more accurate description would reflect the reality of human-assisted machine research, where the computational workload is largely executed by algorithms under human direction. Acknowledging this inversion is essential to ensure transparency, methodological integrity, and proper attribution in modern scientific communication.
The NeoCOAST-2 trial, published in Nature Medicine, evaluates the efficacy and safety of neoadjuvant durvalumab-based combination regimens for resectable stage IIA–IIIB non-small cell lung cancer (NSCLC). This phase II, open-label, multicenter study randomized patients to receive durvalumab either alone or in combination with novel immune modulators, including oleclumab (anti-CD73) or monalizumab (anti-NKG2A), alongside platinum-based chemotherapy prior to surgery. The results demonstrated higher major pathological response (MPR) and pathological complete response (pCR) rates with durvalumab combinations compared to durvalumab plus chemotherapy alone, without compromising surgical feasibility or safety. Most patients proceeded to complete resection, with acceptable perioperative complication rates and no new safety signals.
For CTSNet’s global cardiothoracic surgery audience, this study is particularly relevant as it demonstrates how immunomodulatory combinations can enhance tumor clearance preoperatively while maintaining operability and safety. These findings highlight the evolving role of surgery within multimodal immunotherapy protocols, shaping future standards for curative-intent management of resectable NSCLC.