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Journal and News Scan

Source: Journal of Thoracic Oncology
Author(s): Collaud, Stéphane; Waddell, Thomas K.; Yasufuku, Kazuhiro; Pierre, Andrew F.; Darling, Gail E.; Cypel, Marcelo; Rampersaud, Yoga R.; Lewis, Stephen J.; Shepherd, Frances A.; Leighl, Natasha B.; Cho, John; Bezjak, Andrea; Tsao, Ming Sound; Keshavjee, Shaf; de Perrot, Marc

This article describes outcomes of en bloc resection of superior sulcus tumors invading the spine in 48 pts from multiple centers operated on during a 22 year period. Most pts received induction chemotherapy and radiation therapy. Complete resection was achieved in 88%, and 5-year survival was 61%. Surgical mortality was 6%. The primary determinant of survival was complete response to induction therapy.

Source: Annals of Thoracic Surgery
Author(s): Javariah Siddiqui, Christian P. Brizard, Igor E. Konstantinov, John Galati, Gavin Wheaton, Michael Cheung, Stephen Horton, Yves d'Udekem

Bicuspid AV repair was performed in 146 pts over a period of 34 years; the primary indication was stenosis. Survival at 20 yrs was 88%. Freedom from reintervention at 18 yrs was 43%. 30 additional pts without reintervention had moderate to severe stenosis or moderate regurgitation at last follow-up.

Source: Annals of Thoracic Surgery
Author(s): Ho Young Hwang, Kwang Ree Cho, Ki-Bong Kim

The patency and clinical outcomes of the right internal thoracic artery (RITA) and right gastroepiploic artery (RGEA) as Y-grafts to the LIMA in situ were evaluated in 443 pts using propensity score matching. Graft patency, overall survival, and freedom from reintervention rates were similar for the two groups.

Source: Annals of Thoracic Surgery
Author(s): Bing-sheng Sun, Yue Li, Zhen-fa Zhang, Jian You, Chang-li Wang

Osteopontin (OPN) influences metastatic behavior of tumors through binding to CD44v6 and integrin. The authors in this study assessed OPN and CD44v6 expression in 159 NSCLC pts and evaluated survival. The combination of markers stratified overall and disease-free survival, especially in stage I pts. Overall survival for [OPN- AND CD44v6-] pts was 64.4%, for [OPN+ OR CD44v6+] was 49.1%, and for [OPN+ AND CD44v6+] was 16.4%.

Source: Chest
Author(s): Francisco A. Almeida; Roberto F. Casal; Carlos A. Jimenez; George A. Eapen; Mateen Uzbeck; Mona Sarkiss; David Rice; Rodolfo C. Morice; David E. Ost

Guidelines for evaluation of patients with suspected lung cancer and evidence for mediastinal adenopathy in the absence of distant metastatic disease recommend mediastinal nodal sampling as the initial diagnostic/staging technique. In this study the authors evaluated compliance with that guideline in 137 pts. Guideline-compliant pts underwent 1.3 tests compared to 2.3 tests for guideline-noncompliant pts and experienced fewer complications (0% vs 17%). Most complications were related to unnecessary CT-FNA. Initial EBUS-TBNA was sufficient in 64%. Guideline compliance was only 22%.

Source: New York Times

The New York Times revisits the spiraling increase in health care costs in the United States.

Source: Interactive Journal of Cardiovascular and Thoracic Surgery
Author(s): Yanping Cheng, Michael S. Aboodi, Andrew S. Wechsler, Greg L. Kaluza, Juan F. Granada, Kevin Van Bladel, Lon S. Annest, and Geng-Hua Yi

The authors performed off-pump left ventricular reconstruction for ischemic cardiomyopathy in ovine model applying epicardial catheter-based ventricular reconstruction. Six weeks after ventricular reconstruction end-systolic volume was decreased by 38% and ejection fraction increased by 13%. Histopathology showed appreciable reduction of the chronic infarct in the left ventricle.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Noa Ghersin, Sobhi Abadi, Anat Sabbag, Yehiel Lamash, Robert H. Anderson, Helen Wolfson, and Jonathan Lessick

The authors analyzed cardiac CT scans of 70 patients for the smallest distance between each point on the annulus and each of the left circumflex and right coronary arteries. The global minimum for the left circumflex was <5 mm for about 30% of patients. Knowledge of the exact anatomic relationships could help to reduce iatrogenic complications of mitral annuloplasty.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Marc Riquet, Pierre Mordant, Elizabeth Fabre-Guillevin, Alex Arame, Christophe Foucault, Antoine Dujon, and Françoise Le Pimpec Barthes

The authors present a case series of 11 patients with N3 non-small-cell lung cancer who received multimodality treatment including surgery. They conclude that such regimen is worth to be considered in selected patients.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Suk-Won Song, Kyung-Jong Yoo, Yoo Rim Shin, Sun-Hee Lim, and Bum-Koo Cho

Intermittent lower body perfusion during repair of acute DeBakey type I aortic dissection in moderate hypothermic circulatory arrest (MHCA) seems to be protective against renal failure and increase of liver enzymes compared to MHCA only in a study on 107 patients.