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Journal and News Scan

Source: Circulation Research
Author(s): Roshni Roy Chowdhury, Jessica D’Addabbo, Xianxi Huang, Stefan Veizades, Koki Sasagawa, David M. Louis, Paul Cheng, Jan Sokol, Annie Jensen, Alexandria Tso, Vishnu Shankar, Ben Shogo Wendel, Isaac Bakerman, Grace Liang, Tiffany Koyano, Robyn Fong, Allison Nau, Herra Ahmad, J.K. Gopakumar, Robert Wirka, Andrew Lee, Jack Boyd, Y. Joseph Woo, Thomas Quertermous, Gunsagar Gulati, Siddhartha Jaiswal, Yueh-Hsiu Chien, Charles Chan, Mark M. Davis, Patricia K. Nguyen

Interesting manuscript on the immunology of coronary atheroma, with tanslational potential in therapies and prevention of ischaemic heart disease.

Source: JAMA Surgery
Author(s): Quin JA, Wagner TH, Hattler B, Carr BM, Collins J, Almassi GH, Grover FL, and Shroyer AL.

This 10-year follow-up of the ROBY study reports on the primary end points of all-cause death and the composite of death or revascularization among 2203 patients randomized to off-pump or on-pump CABG 2002-2007.  Death rates at 10 years were 34.2% for off-pump and 31.1% for on-pump.  The composite end point was reached at 4.6 years for off-pump and 5.0 years for on-pump.  The study identified no advantages for off-pump bypass related to these 10-year outcomes.

Source: The Annals of Thoracic Surgery
Author(s): Peter J. Kneuertz, MD Jing Zhao, PhD Desmond M. D’Souza, MD Mahmoud Abdel-Rasoul, MS, MPH Robert E. Merritt, MD

Segmentectomy is rising in popularity as a parenchyma-sparing alternative for anatomic lung resection. This study sought to investigate temporal changes in patient selection, case volume, and outcomes for segmentectomy using the Society of Thoracic Surgeons (STS) National Database.

Source: The Annals of Thoracic Surgery
Author(s): Amanda S. Thomas, MSPH Alice Chan, MD Bahaaldin Alsoufi, MD Jeffrey M. Vinocur, MD Lazaros Kochilas, MD, MSCR

This study both examined the outcomes of children (<18 years) operated on for anomalous left coronary artery from the pulmonary artery (ALCAPA) and linked patients undergoing ALCAPA repair between 1982 and 2003 in the Pediatric Cardiac Care Consortium with the National Death Index and the Organ Procurement and Transplantation Network to examine their outcomes through 2019.

Source: Journal of Thoracic and Cardiovascular Surgery
Author(s): Vincent Chauvette, MD, Ismail Bouhout, MD, Mohammed Tarabzoni, MD, Magali Pham, MD, Daniel Wong, MD, Richard Whitlock, MD, PhD, Michael W.A. Chu, MD, MSc, Ismail El-Hamamsy, MD, PhD, on behalf of the Canadian Ross Registry

This study from the Canadian Ross Registry evaluated 466 consecutive patients who underwent a Ross procedure using a decellularized cryopreserved pulmonary homograft and evaluated for pulmonary homograft dysfunction. They demonstrate that the cumulative incidence of pulmonary homograft dysfunction was 11% at 6 years with pulmonary homograft stenosis (93%)  being the most frequent cause, with an incidence of homograft reintervention of 3% at 6 years. 

Source: The Annals of Thoracic Surgery
Author(s): Austin L. Rogers, MD Robert D. Allman, MD Xiangming Fang, PhD Linda C. Kindell, RN-BSN Leslie W. Nifong, MD Benjamin C. Degner, MD Shahab A. Akhter, MD

The Society of Thoracic Surgeons current (STS) guidelines recommend delaying coronary artery bypass graft surgery (CABG) for several days or performing platelet function testing in stable patients who received P2Y12 inhibitors. Their program routinely uses thromboelastography-platelet mapping (TEG-PM) to expedite CABG in P2Y12 nonresponders. They hypothesize that P2Y12 nonresponders had no difference in length of stay to surgery and blood product transfusion compared with patients undergoing urgent inpatient CABG not treated with a P2Y12 inhibitor.

Source: The Annals of Thoracic Surgery
Author(s): Neel P. Chudgar, MD Roger Zhu, MD Katherine D. Gray, MD Ryan Chiu, MD, MBA Araceli Delacruz Carrera, DNP Samuel J. Lang, MD Dimitrios V. Avgerinos, MD, PhD Charles A. Mack, MD

Readmission after coronary artery bypass grafting (CABG) is linked with negative outcomes and raised cost. We evaluated the impact of a high-value care discharge protocol on readmission, length of stay (LOS), and discharge destination in patients undergoing isolated CABG.

Source: Circulation Research
Author(s): Olurotimi O. Mesubi , Mark E. Anderson

A brief but comprehensive editorial on nuances of the links between atrial fibrillation and heart failure, apropos a trial we have commented recently on, by the Johns Hopkins team that develops the calmodulin-dependent protein kinase II inhibitor molecules 

 

Source: Brazilian Journal of Cardiovascular Surgery
Author(s): Kevin Pilarczyk1,2, MD; Vinicius Nina3,4, MD; Lynn Boshkov5, MD; Barbara Ferdman6, MD; Emily A. Farkas7, MD; Nicole Burnham8, MD; Renzo Cifuentes9, Daniel Ntogwiachu10, MD; Aubyn Marath4, MD

Every year, millions of people are dying and millions more are disabled due to treatable cardiovascular diseases. Surgical capacity is unevenly distributed around the world and disproportionally affects populations in low- and middle- income countries (LMICs). COVID-19 increases barriers for access to cardiac surgical care, and high- level action is urgently needed to not only expand cardiac services around the world but also to ensure health systems are strengthened so that cardiac patients can be effectively managed during and after the pandemic. The primary aim of this systematic review is to provide perioperative strategies to help restore or preserve cardiovascular services in LMICs under threat from financial and personnel constraints imposed by the pandemic.

 

Source: Circulation Research
Author(s): Luca Zanoli, Agostino Gaudio, Dimitri P. Mikhailidis, Niki Katsiki, Niccolò Castellino, Lorenzo Lo Cicero, Giulio Geraci, Concetto Sessa, Letizia Fiorito, Francesca Marino, Maria Antonietta Di Rosolini, Michele Colaci, Antonio Longo, Arturo Montineri, Lorenzo Malatino , Pietro Castellino and Methuselah Study Group

Interesting case-control study on variations of aortovascular compliance 

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