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Cardiac - Pharmacology

February 14, 2015
The author presents credible (and enticing) evidence for eating dark chocolate for health reasons, including managing hypertension and cardiovascular disease.
February 10, 2015
Dr. Reed et al from the Cleveland Clinic conducted this prospective study to assess whether VerifyNow point-of-care platelet testing could predict bleeding in 39 patients receiving Plavix and undergoing CABG.  Patients in higher PRU quartiles experienced smaller decreases in hematocrit and less bleeding.
February 5, 2015
In this recently published clinical study investigators from Columbia University, New York Presbyterian Hospital evaluated the safety of Del Nido cardioplegia in high-risk CABG surgery after AMI.
December 19, 2014
A $400,000 grant from the MacArthur Foundation will be used to create a database of retractions from scientific journals, extending the work done by  Adam Marcus
December 3, 2014
This study determined the relationship of pre-hospital use of epinephrine during resuscitation to survival in patients who experienced return of spontaneous circulation after out of hospital cardiac arrest. 73% received epinephrine, and 17% of those patients experienced a good outcome (discharged alive with good neurologic status). 
June 1, 2014
This study assessed whether the application of a poly based hydrogel containing amioderone applied to the epicardium at the time of surgery reduced the incidence of post-operative atrial fibrillation. The study randomised 100 patients undergoing cardiac surgery to either receive the amioderone spray at the time of surgery or no intervention.
May 5, 2014
This is a really nice summary article of the new oral antocoagulants which is freely available in full.  It describes the particular complications of the NOAC and cautions in renal failure and recommends safe stopping times before surgery 
April 1, 2014
This randomized trial including more than 10,000 patients undergoing noncardiac surgery evaluated the use of perioperative aspirin in patients at increased risk for vascular complications. The end points were death or MI. The end points occurred in equal numbers (7%) in both groups.
March 26, 2014
The PROACT trial is evaluating the clinical utility and safety of less aggressive anticoagulation schemes after bileaflet AVR. This arm of the trial compared low dose (INR 1.5-2.0) to standard dose (INR 2.0-3.0)warfarin.

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