This retrospective single institution study evaluated the relationship between radiation dose to the gastric fundus and the incidence of esophageal anastomotic leak after esophagectomy for cancer. The leak rate was 26%. Pts with a leak had a significantly higher RT dose to the gastric fundus. Using a cut point of 31.4 Gy, leak rates were 43% vs 15
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Esophagus - Cancer
November 23, 2016
Is Centralization Needed for Esophageal and Gastric Cancer Patients With Low Operative Risk?: A Nationwide Study
October 15, 2016
All patients undergoing surgical therapy for esophageal or gastric cancer in France 2010-2012 were evaluated for postoperative mortality stratified by comorbidity score and assessed by medical center volume (low, medium, high, very high). Most operations were performed in low volume centers.
Prognostic Significance of the Location of Lymph Node Metastases in Patients With Adenocarcinoma of the Distal Esophagus or Gastroesophageal Junction
October 15, 2016
The authors explored the relationship of nodal region and survival from adenocarcinoma of the esophagus/GEJ in patients undergoing induction therapy and transthoracic resection.
October 15, 2016
In this retrospective review, the authors queried whether a hiatal hernia (HH; >5cm) was associated with adverse outcomes after esophagectomy for cancer. After adjustment, they found that HH patients had a lower rate of complete resection and lower median survival.
Baseline measure of health-related quality of life (Functional Assessment of Cancer Therapy-Esophagus) is associated with overall survival in patients with esophageal cancer
May 5, 2016
In this multicenter study, baseline QOL was assessed in over 200 patients with stage II or III esophageal cancer who underwent induction therapy and surgery or definitive chemoradiotherapy. Baseline QOL was related to survival independent of age, stage, histologic type, and treatment. It is suggested that assessment of baseline QOL is a prognostic
Preoperative Chemoradiation Therapy Versus Chemotherapy in Patients Undergoing Modified En Bloc Esophagectomy for Locally Advanced Esophageal Adenocarcinoma: Is Radiotherapy Beneficial?
April 12, 2016
Whether adding radiotherapy to induction chemotherapy prior to esophagectomy adds a survival benefit is uncertain. The authors assessed outcomes of 214 patients with T3N1M0 adenocarcinoma among three institutions who underwent induction therapy followed by esophagectomy. 114 patients had chemotherapy and 100 patients had chemoradiotherapy. 90-day
April 5, 2016
This video demonstrates an esophageal replacement with a long segment super-charged jejunal interposition.
March 17, 2016
This video shows an example of a transthoracic robotic resection of an esophageal leiomyoma.
Use of Positron Emission Tomography to Detect Recurrence and Associations With Survival in Patients With Lung and Esophageal Cancers
February 24, 2016
Routine use of PET scans to follow up asymptomatic patients do not affect survival, according to this retrospective analysis of a cohort of 97,152 lung cancer and 4,446 esophageal cancer patients. They compared high and low level of use of PET centers, and found no differences in two-year survival.
Doubling of 30-Day Mortality by 90 Days After Esophagectomy: A Critical Measure of Outcomes for Quality Improvement
January 12, 2016
30-day and 90-day mortality rates were compared using information from the National Cancer Data Base 2007-2011. Among nearly 16,000 esophagectomies, the 30-day mortality rate was 4.2% and the 90-day rate was 8.9%. 90-day mortality was uniquely associated with tumor location, tumor stage, and receipt of neoadjuvant therapy.