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Lung - Basic Science

January 21, 2022
An editorial  with some interest for the cardiothoracic surgeon, in particular the awareness of changes in the right vantricle during ECMO support , mostly drawn from the recent Covid experiences, and with a useful paragraph on veno-pulmonary arterial ECMO, discussing the uncoupling of RV and PA. 
July 14, 2020
A small histopathological study of SARS and influenza autopsies compared to rejected for transplantation lungs. There is some speculation on the popular procoagulopathic nature of the panvirus, based on expression of angiotensin converting enzyme 2.There might be a collateral stimulus for lung preservation in organ retrieval.
February 3, 2020
This interesting study compared bronchial epithelial mutation burden, the primary source of new lung cancers, among nonsmokers, former smokers, and current smokers.  Smoking typically adds 1,000 to 10,000 mutations per cell.  Smoking cessation in this study was associated with replenishment of the abnormal epithelium with cells that are typical of no
August 20, 2019
Interesting follow-up study of 208 pulmonary ground -glass opacities in 160 subjects, with a yield of three adenocardinomas.
August 14, 2019
A comprehensive audio lecture from an academic pathologist on non-malignant pulmonary lesions.
October 10, 2018
A brief viewpoint article (by the savior of baby Esperanza) from a widely read non-surgical journal on the debate on ECMO/EOLIA. I assume  'thoracotomy' implies 'sternotomy' as the standard surgical approach for ECMO cannulation in adults and larger children. 
September 13, 2018
Exciting debate on the EOLIA trial! https://www.ctsnet.org/jans/extracorporeal-membrane-oxygenation-severe-a...
August 31, 2018
Quite useful case-illustrated debate on a VERY hot topic!
August 13, 2018
The 5-year survival rate in patients after curative surgery for N0 nonsmall cell lung cancer (NSCLC) is reduced by recurrence and metastasis, and there is evidence that the epithelial–mesenchymal transition in cancer cells is associated with metastasis.

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