The UNOS donor heart allocation system was revised in 2018, giving priority to patients on inpatient mechanical circulatory support (MCS). Patients admitted with heart failure-associated cardiogenic shock were tracked for the frequency of use of mechanical circulatory support before and after implementation of this change. In non-transplant center
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Use of Temporary Mechanical Circulatory Support for Management of Cardiogenic Shock Before and After the United Network for Organ Sharing Donor Heart Allocation System Changes
April 16, 2020
April 9, 2020
Another refreshing change of pace with an interesting pre-translational contibution to the genetics of atrial dysrhythmias.
In Situ Expansion, Differentiation and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoid
April 2, 2020
Quite refreshing well-written experimental paper leaving promises of artificial organoids.
American Association for Thoracic Surgery/International Society for Heart and Lung Transplantation Guidelines on Selected Topics in Mechanical Circulatory Support
January 30, 2020
The American Association for Thoracic Surgery and International Society for Heart and Lung Transplantation provide a consensus guidelines document on ten important aspects in mechanical circulatory support. These include:
December 4, 2019
Succinct commentary on the challenge of vascular access in ECMO circuits on the occasion of a manuscript on a novel design of a multi-access adaptor.
October 14, 2019
An extremely interesting research question abutting cardiac physiology, and a manuscript that may generate future additional clinical research.
October 12, 2019
The association of cardiovascular events and all-cause mortality with optimism was assessed in this meta-analysis. Optimism was associated with a decreased risk of cardiovascular events (ROR 0.65) and a decrease in all-cause mortality (RR 0.86). Mechansims have yet to be identified.
CABG Improves Outcomes in Patients With Ischemic Cardiomyopathy: 10-Year Follow-Up of the STICH Trial
September 14, 2019
This study reports ten year outcomes of the STICH trial. Comparing CABG to medical therapy groups, the authors note that CABG reduced all cause, cardiovascular, and heart failure hospitalizations. This included time-to-first and recurrent events. This was due to fewer total cardiovascular hospitalizations, the majority due to heart failure.
August 31, 2019
The growth and replication of cardiomyocytes derived from stem cells is insufficient to permit regeneration of functioning heart tissue. In this study, the authors used stem cell-derived epicardial cells to facilitate myocardial regeneration.
August 23, 2019
Excellent and brief summary of the debate on functional mitral regurgitation on mechanical support.