In this manuscript, the authors offer a comprehensive and thorough review of the pathophysiology of aortic stenosis and relate this to the different potential medical treatment options to slow down the progression of the disease.
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Basic science
August 8, 2016
This is a retrospective study comparing outcomes of conventional 1:4 cardioplegia vs 4:1 Del Nido cardioplegia on adult patients undergoing CABG. 249 consecutive patients underwent coronary artery bypass using blood cardioplegia and 159 using del Nido Cardioplegia.
August 8, 2016
A bona fide new technique applied in a handful of low-risk deep sternal wound infections. It will be interesting to see the follow-up and perhaps some cardiothoracic surgical input to the efforts of the esteemed plastic surgical colleague who is the sole author.
July 13, 2016
The authors enrolled 149 patients on DAPT undergoing urgent cardiac surgery in a prospective study analyzing the association between platelet reactivity and postoperative bleeding. They found that decreasing platelet reactivity correlated with an increase in calculated red blood cell loss after surgery.
May 8, 2016
The entire issue is dedicated to thrombosis and makes a compulsory read for cardiovascular and thoracic hospitalists. Of patricular relevance to the thoracic surgeon are the translational articles on system analysis (page 1348) and the table on oral anticoagulants on page 1410.
March 27, 2016
Norepinephrine is often used to maintain the mean pressure during open heart surgery but it is said that it could constrict cerebral arteries, reducing cerebral blood flow. Is it true? The authors explored the association of Norepi doses and rSO2 measured using near-infrared spectroscopy.
March 25, 2016
An overview of the basic pharmacology of commonly used cardiovascularly active drugs.
March 24, 2016
For you chocolate lovers out there, hard evidence that dark chocolate can boost endurance performance.
March 4, 2016
Lactic acidosis is a very common biological issue for the postoperative patient with shock. This very nice review addresses thehemodynamic consequences of shock-associated lactic acidosis and highlights the various therapeutic options that can be considered by the bedside clinician.
February 20, 2016
A succinct editorial from a British academic transplant surgeon. It discusses the need for stratifying the utilization of donor lungs based on recent and previous retrospective papers from North American and European databases. Professor Dark also briefly debates the needs for research on assessing and optimizing the organs.