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Does Platelet Reactivity Predict Bleeding in Patients Needing Urgent Coronary Artery Bypass Grafting During Dual Antiplatelet Therapy?

Wednesday, July 13, 2016

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Source

Source Name: Annals of Thoracic Surgery

Author(s)

Elisabeth Mahla, MD, Florian Prueller, MD, Sylvia Farzi, MD, Gudrun Pregartner, MSc, Reinhard B. Raggam, MD, Elisabeth Beran, MD, Wolfgang Toller, MD, Andrea Berghold, PhD, Udaya S. Tantry, PhD, Paul A. Gurbel, MD

The authors enrolled 149 patients on DAPT undergoing urgent cardiac surgery in a prospective study analyzing the association between platelet reactivity and postoperative bleeding.  They found that decreasing platelet reactivity correlated with an increase in calculated red blood cell loss after surgery.  Their findings support the use of objective measures of platelet function prior to proceeding with cardiac surgery.

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