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Basic science

May 22, 2017
A surprisingly readable Australasian manuscript on risk prediction models for cardiac surgery. Interesting that the class of dyspnoea was not captured in 5.28% of the operated patients.
May 12, 2017
A short and readable commentary on monoclonal antibodies and dyslipidaemias, particularly on FOURIER,  SPIRE and ODYSSEY trials
May 11, 2017
I was moved by this editorial on global health matters in a daily British newspaper by an  academic medical  colleague,  written in response to anticipated changes in the leadership of the  World Health Organisation. It is perhaps time for us surgeons to augment our administrative participation in global healthcare. 
May 8, 2017
Researchers conducted a  study, published in Nature, to investigate whether this genetic diversity could be tracked clinically.
April 29, 2017
A succinct update relevant to all arrhythmia and heart failure surgeons. The concept of atrial cardiomyopathy is particularly stimulating.
March 17, 2017
Three quarters of a century in caring for patients with congenital heart disease are summarized well in this brief viewpoint article, with the big data issue discussed.
January 10, 2017
A comprehensive discussion on an important parameter for cardiologists and surgeons dealing with congenital and structural / valve disease, as applicable to the systemic circulation 
December 30, 2016
A most easily read brief editorial explaining in simple terms the power of a study, bootstrapping and the CLINICAL significance of risk factors in multivariate analysis. The author explains that the number of events defines the effective desirable sample size, not the number of individuals included in studies.
December 22, 2016
Physiologic changes associated with sympathectomy for palmar hyperhidrosis were assessed in this randomized trial comparing T3 ganglionectomy to division of the sympathetic chain at T2 and T3.  Outcomes were assessed using Holter monitoring.  Clinical outcomes were similar between the groups.  Electrophysiologic changes representing vagal activity me
December 22, 2016
This retrospective study compared Celsior (65% of pts) to all-blood continuous myocardial protection (35%) in 631 patients undergoing elective aortic valve replacement.  Troponin T release was lower in Celsior patients, as was the risk of postoperative death (OR 0.33; 0.15 - 0.76).  Other outcomes were similar between the groups.

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