ALERT!

This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Cancer

September 27, 2015
One fourth of lung cancer patients are never smokers, consisting of 53% of women with lung cancer and 15% of men; the majority of these are adenocarcinomas. Estrogens interact with two types of receptors, ERα and ERβ, and may play a role in the development of lung cancer.
September 21, 2015
In this video, the authors demonstrate their first robotic left pneumonectomy for a pT2N1 neoplasm.
September 20, 2015
A large retrospective study comparing 117618 patients from the National Cancer Database with Stage I NSCLC. 111731 received surgery, 5887 received SBRT. In a propensity managed comparison, those undergoing surgery had increased overall survival.
September 16, 2015
Outcomes of the California Cancer Registry for patients undergoing resection for Stage I NSCLC were evaluated according to Commission on Cancer (CoC) accreditation status and lung resection procedure volume.  High volume hospitals (>50 annually) had better survival compared to medium (20-50 annually; HR 1.23) and low volume (<20 annually; 1.77)
September 16, 2015
The 6th and 7th versions of the AJCC staging system were compared for their prognostic accuracy for patients with esophagogastric adenocarcinomas using an institutional database.  The 7th edition system was significantly more accurate in groups undergoing MIE, induction therapy, and overall.
September 12, 2015
This randomized trial compared induction therapy for pathologically-proven N2/IIIA NSCLC with 3 cycles of cisplatinum and docetaxel chemotherapy alone to chemotherapy combined with 44 Gy of radiation therapy.  232 pts in 23 centers were enrolled over a 12 year period.  No differences were identified in the chemotherapy vs chemoradiotherapy groups for
September 8, 2015
This single institution study involving 606 patients operated 2000-2012 examined the influence of the extent of lymphadenectomy on survival.  The number of nodes resected was not related to all-cause mortality, even comparing the highest and lowest quartiles.  The number of metastatic nodes and an increasing ratio of positive to negative nodes were e
September 4, 2015
This study used a multicenter cohort in Italy to identify prognostic indicators for 3-year survival in patients who had undergone extrapleural pneumonectomy (EPP) for mesothelioma.  23% lived 3 years or longer.  This survival was related to age, epitheliod histology, lack of asbestos exposure, and involved LN ratio.  A risk score for survival was dev
August 26, 2015
Investigators from Stanford developed a nine-gene expression predictor for survival outcome in early-stage nonsquamous NSCLC. They developed and validated a quantitative real-time polymerase chain reaction assay easily applicable to routinely obtained paraffin-embedded tumor specimens.
August 22, 2015
This comprehensive review outlines changes in the WHO classification of lung tumors, chagnes that will affect our clinical practice in the near future.

Pages