This meta-analysis evaluated results from 6 studies totalling 868 patients randomized to local control (radiotherapy vs surgery) after induction therapy for NSCLC with N2 disease. Four studies evaluated induction chemotherapy, the other 2 evaluated induction chemoradiotherapy. Differences in outcomes were not significant, but there was a strong tre
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Cancer
July 9, 2015
Stephen Hazelrigg, Neil Christie, and Hiran Fernando discuss the use of stereotactic body radiation therapy (SBRT) in the treatment of lung cancer.
July 1, 2015
This video presents a single-port VATS right upper lobe sleeve lobectomy for a stage I carcinoid tumor in a 52-year-old patient. Sleeve lobectomy is a challenging and complex procedure. Typical carcinoids occluding the right upper lobe bronchus present an ideal opportunity for sleeve upper lobectomy due to their indolent nature and excellent oncologic outcomes.
June 28, 2015
Retrospective cross-sectional cohort study using 5 years of Medicare benficiary data to determine whether post discharge mortality varies by time-to-readmission. Two of the three operations analyzed were lung resection (n=101,092) and coronary artery bypass grafting (CABG) (n=484,260).
June 25, 2015
This study evaluated outcomes in patients undergoing resection for lung cancer who were found at surgery to have pleural carcinomatosis. 2.9% of registry patients were identified, of whom 49% had a macroscopic complete resection. 5-year survival in those without other metastatic disease was 29%. 5-year survival in those undergoing macroscopic comp
June 24, 2015
The ELCAP data set was evaluated for pts identified with non-solid nodules at baseline or during follow-up. 2392 (4.2%) pts had nonsolid nodules at baseline, of which 73 were diagnosed as adenocarcinoma. A new nodule was identified in an additional 485 (0.7%) pts, of whom 11 were diagnosed with adenocarcinoma. Nonsolid nodules improved in 66% of
June 23, 2015
This video demonstrates the performance of a VATS trisegmentectomy on a patient with a left upper lobe cT1aN0 adenocarcinoma.
June 16, 2015
Data from a variety of US sources were used to estimate the contribution of smoking to mortality for 12 common malignancies (colorectal, esophagus, kidney, larynx, liver, lung, leukemia, head/neck, pancreas, stomach, bladder, cervix. The contribution of smoking to mortality ranged from 10% (colorectal) to 77% (larynx). The overall contribution was
June 14, 2015
Trials evaluating the use of surgery in stage IIIB NSCLC are lacking. This study goes some way to address that and demonstrates that surgery as part of multi-modality therapy may result in a survival benefit.
June 12, 2015
This meta-analysis of published studies evaluated outcomes of multimodality therapy including resection for superior sulcus NSCLC invading the spine. 134 articles were evaluated, which included 135 patients. 63% had induction therapy, and all underwent en bloc resection. 52% had adjuvant therapy. Survival at 3,5, and 10 years was 57%, 42%, and 27