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Cancer

June 12, 2015
Outcomes of esophagectomy, including in-hospital mortality and length of stay (LOS), were compared between England (centralized care) and the US (no centralized care).  Data for 2005-2010 included 7433 esophagectomies performed in 66 hospitals in England and 5858 esophagectomies performed in 775 hospitals in the US.  Morality was greater in the US (5
June 12, 2015
Laser-assisted fluorescent-dye angiography (LAA) was used prospectively in 150 patients undergoing esophagectomy with gastric pull-up to assess blood flow in the gastric tube.  Anastomotic leak occured in 17%.  Anastomoses performed in areas of normal perfusion had a 2% leak rate, compared to a 45% leak rate when anastomoses were performed in areas o
June 11, 2015
This single institution retrospective analysis of esophagectomy or gastrectomy for GEJ cancer compared outcomes between groups who did and did not complete recommended 2 cycles of postoperative adjuvant chemotherapy.  Of 110 pts who underwent perioperative chemotherapy, 67% completed postoperative adjuvant chemotherapy.  Completion of 2 cycles or mor
May 28, 2015
In presentations given at the 2014 STSA Annual Meeting in Tucson, Arizona, two experts address lung cancer screening.
May 22, 2015
In this retrospective review of 336 patients treated surgically for early stage NSCLC, the prognostic value of PET SUV was evaluated.  Risks of recurrence and death increased steadily as SUV increased. 
May 22, 2015
This interesting article summarizes the potential benefits of exercise in patients with lung cancer, including improved exercise capacity and quality of life, and reduced postoperative complications and length of postoperative stay.  This modality is safe, and is likely underutilized in this patient population.
May 20, 2015
A pooled analysis of outcomes from two randomized trials involving SBRT or surgery for operable patients with clinical early stage NSCLC was performed. The number of patients was small (58 total) and the follow-up was a median of 35-40 mos.  Overall 3-year survival was better in the SBRT group (95% vs 79%; p=0.037) whereas recurrence free survival di
May 19, 2015
Pts with suspected lung cancer underwent sampling of normal-appearingbronchial epithelial cells in the main bronchi, unrelated to the suspected tumor.  Gene expression was analyzed and classified.  Classification for cancer was about 75% accurate. 
May 17, 2015
The most recent WHO classification for lung adenocarcinoma is based on the predominant histologic subtype in the resected tumor. Several studies have validated the use of this classification system for  prognostic purposes, but predicting response to adjuvant chemotherapy has not yet been tested.
May 17, 2015
In this population-based cohort study with 1044 patients who underwent esophagectomy for esophageal cancer between 1987 and 2010 in Sweden, the researchers found that a higher number of lymph nodes removed did not affect mortality in any specific stage.

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