The PORTICO trial has opened to evaluate the Portico Transcatheter Aortic Valve System. This prospective multicenter trial involving up to 40 sites will randomize pts to Portico vs another TAVR valve in the US.
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Cancer
May 21, 2014
May 15, 2014
Betty Tong, Co-Director of the Lung Cancer Screening Program at Duke University Medical Center, discusses the process of establishing a lung cancer screening program.
May 9, 2014
Using the Nationwide Inpatient Sample, the authors evaluated outcomes and costs of VATS (37,595) vs robotic (2,498) lobectomy 2008-2011. Robotic lobectomy was associated with higher rates of complications, particularly cardiovascular and iatrogenic bleeding, and higher costs ($22,582 vs $17,874).
May 6, 2014
67 patients without a previous history of lung cancer underwent FNA of a GGO with results suspicious for, but not diagnostic of, adenocarcinoma. 47 pts who elected to undergo resection were compared to 16 who opted for observation. 6/16 observed pts developed interval growth or increase in the solid component of the GGO and 5 underwent resection or
May 6, 2014
Clinical outcomes of patients with lung adenocarcinoma were analyzed with respect to the histologic subtype of adenocarcinoma. Histologic pattern was associated with sex, T status, N status, and stage. Recurrence was higher in patients with micropapillary and solid tumors.
May 3, 2014
This systematic review and meta-analysis of individual patient data from 15 RCTs (2385 pts) assessed the utility of preoperative chemotherapy in patients with primarily stages Ib-IIIa NSCLC. Chemotherapy resulted in a 13% reduction in death (HR 0.87, p=0.007), and a 5% survival improvement at 5 years.
May 1, 2014
A panel for the Centers for Medicare and Medicaid determined that annual low-dose CT screening for lung cancer carries too high a risk related to the potential benefits. They expressed concern about high false-positive rates, quality assurance, and gaps in evidence as to how the CT results would be used. Despite the fact that many professional grou
April 21, 2014
This video demonstrates a left video-assisted thoracoscopic sleeve lower lobectomy in a 68-year-old male smoker with an endobronchial squamous cell carcinoma of the left lower lobe.
Transcriptomic Architecture of the Adjacent Airway Field Cancerization in Non–Small Cell Lung Cancer
April 14, 2014
In this promising investigation, authors have found changes associated with airway cancerization in large airways in lung cancer patients, while these changes are absent in cancer-free smokers. And in addition, with shorter distance from tumors, airway cancerization expression increases statistically.
March 27, 2014
The authors review 17 publications on the use of artificial chordae in mitral valve repair. Rates of mortality, morbidity, complications and reoperation are low. Correct determination of the length of the chordae presents still one of the most important problems.