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Cancer

June 22, 2014
This multicenter prospective study evaluated indications for and outcomes of ICU admission for 449 patients with lung cancer.  Most patients had a newly diagnosed lung cancer, and the most common indication for ICU admission was airway compromise.  Hospital and 6-month mortality rates were 39% and 55%.  Determinants of mortality were severity of orga
June 20, 2014
Bilobectomy and right lobectomy were compared in a retrospective case-control study with 117 matched pairs. Space-mismatch related complications were not more frequent following bilobectomy, however, the rate of cardiovascular events was higher after lower and middle lobectomy compared with lower lobectomy.
June 17, 2014
In this video, a single 3.5 cm incision was used for a VATS right upper lobectomy and lymph node dissection for non-small cell carcinoma in a 61-year-old female patient. The incision was only slightly larger than a chest tube insertion incision.
June 10, 2014
This report on 127 pts with atypical pulmonary carcinoid evaluated clinical and pathological prognostic features.  Recurrence developed in 25% of pts during follow-up, with sublobar resection being the only independent predictor.  Survival was related only to distant recurrence on multivariable analysis.  The authors recommend complete standard anato
May 29, 2014
This retrospective review included 322 pts undergoing open esophagectomy 2005-2010.  Gastric empyting procedures included Botox (78), pyloroplasty (199), and pyloromyotomy (45).  Botox was associated with more postop reflux symptoms and required more prokinetic agents.
May 29, 2014
This multicenter retrospective review included 518 pts from 9 centers who underwent EPP from 2000 to 2010.  Half the pts received induction chemotherapy, and nearly three-quarters of the patients received postoperative adjuvant therapy, primarily chemotherapy.  The major surgical complication rate was 26% and 90 day mortality was 6.9%.  3-year surviv
May 28, 2014
  Extracapsular spread of cancer cells is associated with poorer outcome compared to intracapsular limitation in positive lymphnodes in patients with adenocarcinoma of the oesophagus and gastro-oesophageal junction. This finding is not reflected by the current tumour staging system.  
May 27, 2014
This metanalysis identified 26 eligible studies that assess the predictive value of PET for survival after induction therapy.  Complete metabolic response was associated with a 50% decrease in mortality and in tumor recurrence compared to no response.   
May 27, 2014
This retrospective single institution review assessed the incidence of hiatal hernia after minimally invasive esophagectomy (MIE).  Of 114 patients followed, 9 (8%) developed herniation, of whom 5 were symptomatic.  All were repaired laparoscopically, except 2 who underwent emergent surgery, with good results.
May 22, 2014
David Sugarbaker, Director of the International Mesothelioma Program, discusses the use of extrapleural pneumonectomy in the treatment of mesothelioma.

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