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Esophagus

July 12, 2014
This single institution study evaluated differences in 30-day and 90-day mortality after esophagectomy in nearly 1300 patients.  30-day mortality was 2.9%, hospital mortalit was 5.1%, and 90-day mortality was 7%.  Late deaths were related to surgery (particularly the occurrence of anastomotic leakage), sudden death, and recurrent cancer.  The sensiti
July 12, 2014
A risk model of mortality associated with esophagectomy in Japan was developed using variables identified in the ACS NSQIP program.  30-day and overall surgical mortality rates were 1.2% and 3.4%, and the morbidity rate was 42%.  Morbidity was higher after minimally invasive esophagectomy.  Mortality was related to difficulty with ADLs, recent smokin
July 12, 2014
This editorial, authored by a number of presidents/leaders of prominent medical societies, laments a recent position paper of the ESMO espousing medical oncologists as the natural team leaders of multidisciplinary oncologic care.  It cautions other cancer specialists not to abandon their roles as advocates for their cancer patients.
July 1, 2014
In this randomized trial involving195 pts from 30 centers, pts underwent chemoradiotherapy followed by surgery or surgery alone for stage I or II esophageal cancer.  The median follow-up was 94 months.  80% of pts had clinical stage II disease.  R0 resection rate and 3-year survival were similar between the groups.  Induction therapy was associated w
June 22, 2014
This prospective study evaluated the relationship of inflammatory gene polymorphisms and postoperative pneumonia after esophagectomy in 120 pts.  One genotype for IL-10 was significantly associated with reduced postoperative serum IL-10 levels and an increased rate of postoperative pneumonia.  IL-10 polymorphism was an independent predictor of pneumo
June 12, 2014
Francis Nichols of the Mayo Clinic discusses use and implantation techniques of a LINX device to manage gastro-esophageal reflux disease (GERD).
June 10, 2014
Dawn Jaroszewski, Assistant Professor at the Mayo Clinic (Arizona), discusses the potential advantages of minimally invasive esophagectomy (MIE) over open esophagectomy, and shares the Mayo Clinic’s current method for MIE.
June 5, 2014
This article describes a simplified Collis gastroplasty technique performed via left chest, which negates the need for wedge fundectomy. This technique potentially saves OR time and cost, while hypothetically reducing morbidity.
May 29, 2014
This retrospective review included 322 pts undergoing open esophagectomy 2005-2010.  Gastric empyting procedures included Botox (78), pyloroplasty (199), and pyloromyotomy (45).  Botox was associated with more postop reflux symptoms and required more prokinetic agents.
May 28, 2014
  Extracapsular spread of cancer cells is associated with poorer outcome compared to intracapsular limitation in positive lymphnodes in patients with adenocarcinoma of the oesophagus and gastro-oesophageal junction. This finding is not reflected by the current tumour staging system.  

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