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Extended Release of Perioperative Immunotherapy Prevents Tumor Recurrence and Eliminates Metastases

Friday, March 23, 2018

Submitted by

Mark Ferguson

Source

Source Name: Science Translational Medicine

Source URL: http://stm.sciencemag.org/content/10/433/eaar1916

Author(s)

Chun Gwon Park, Christina A. Hartl, Daniela Schmid, Ellese M. Carmona, Hye-Jung Kim, Michael S. Goldberg

Surgery for cancer is known to suppress immune response and facilitate the development of metastases. In this study in mice, a scaffold designed to release agonists of innate immunity over time was placed in the bed of resected tumors. The treatment reduced local recurrence and improved survival.