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Impact of Adjuvant Treatment for Microscopic Residual Disease After Non-Small Cell Lung Cancer Surgery

Monday, February 2, 2015

Submitted by

Mark Ferguson

Source

Source Name: Annals of Thoracic Surgery

Source URL: http://www.annalsthoracicsurgery.org/article/S0003-4975(14)01846-3/abstract

Author(s)

Jacquelyn G. Hancock, Joshua E. Rosen, Alberto Antonicelli, Amy Moreno, Anthony W. Kim, Frank C. Detterbeck, Daniel J. Boffa

The authors queried the National Cancer Data Base to assess outcomes of patients with R1 resection margins related to the presence and type of postoperative adjuvant therapy. 3.1% of over 54,000 resections had R1 margins, which negatively affected long-term survival. Combined chemotherapy and radiation therapy improved outcomes; administration of chemotherapy or radiation therapy alone had a lesser impact on survival.