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Lung volume reduction coil treatment for patients with severe emphysema: a European multicentre trial
LVR using endobronchial therapies remains experimental. This multicenter study tested LVR coils in 60 pts for safety and efficacy. There were a total of 18 serious adverse events. At 6 and 12 mos, dyspnea scores decreased 11%, 6 min walk increased 30-50 m, and FEV1 increased 0.11 L. Pts with either heterogeneous or homogeneous emphysema appeared to improve.