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Postoperative Radiotherapy is Associated with Better Survival in Non–Small Cell Lung Cancer with Involved N2 Lymph Nodes: Results of an Analysis of the National Cancer Data Base

Saturday, February 21, 2015

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Source Name: Journal of Thoracic Oncology


Mikell, John L.; Gillespie, Theresa W.; Hall, William A.; Nickleach, Dana C.; Liu, Yuan; Lipscomb, Joseph; Ramalingam, Suresh S.; Rajpara, Raj S.; Force, Seth D.; Fernandez, Felix G.; Owonikoko, Taofeek K.; Pillai, Rathi N.; Khuri, Fadlo R.; Curran, Walter J.; Higgins, Kristin A.

Indications for postoperative radiation therapy (PORT) for resected lung cancer are unclear.  This study evaluated outcomes from the National Cancer Data Base 2004-2006, including 2115 patients resected with pathologic N2 NSCLC, of whom  918 (43%) received PORT.  PORT was associated with better median survival (42 vs 38 mos, p=0.048) and was associated with improved survival on multivariable analysis.

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