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Prosthesis–Patient Mismatch After Transcatheter Aortic Valve Implantation

Sunday, March 20, 2016

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Source Name: Annals of Thoracic Surgery


Hisato Takagi, MD, PhD, and Takuya Umemoto, MD, PhD, for the ALICE (All-Literature Investigation of Cardiovascular Evidence) Group

This instructive paper includes three separate meta-analyses focusing on patient-prosthesis mismatch (PPM) after TAVR.  These meta-analyses revealed the following:

  • The incidence of PPM after TAVR is 35% (moderate 27%, severe 8%).
  • The incidence of PPM after TAVR is significantly less than that for SAVR, with an OR of 0.23.
  • PPM after TAVR does not seem to impact survival at a mean follow-up interval ranging from 18 months to 4 years.

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