This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

A Randomized Clinical Trial of Red Blood Cell Transfusion Triggers in Cardiac Surgery

Thursday, August 17, 2017

Submitted by


Source Name: Annals of Thoracic Surgery


Colleen G. Koch, MD, MBA, Daniel I. Sessler, MD, Edward J. Mascha, PhD, Joseph F. Sabik III, MD, Liang Li, PhD, Andra I. Duncan, MD, Nicole M. Zimmerman, MS, Eugene H. Blackstone, MD

The Cleveland Clinic group performed a randomized clinical trial comparing transfusion triggers of 24% vs. 28% from 2007-2014.  The study included 722 patients who underwent either CABG or valve surgery.  While the lower trigger group received fewer transfusions, adverse outcomes did not differ between the groups.  Because the lower trigger group had equivalent outcomes but fewer transfusions, the authors recommend using a lower trigger perioperatively.

Add comment

Log in or register to post comments