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Serum Biomarkers May Prognosticate Recurrence in Node-Negative, Non-Small Cell Lung Cancers Less Than 4 Centimeters

Tuesday, October 31, 2017

Submitted by

Mark Ferguson

Source

Source Name: The Annals of Thoracic Surgery

Source URL: http://www.annalsthoracicsurgery.org/article/S0003-4975(17)30918-9/fulltext

Author(s)

Christopher W. Seder, Andrew T. Arndt, Lia Jordano, Sanjib Basu, Cristina L. Fhied, Selina Sayidine, Gary W. Chmielewski, Kelsey Gallo, Michael J. Liptay, Jeffrey A. Borgia

In this single institution study, the authors screened biorepository materials obtained from patients undergoing resection for early stage cancer. They wished to identify serum markers related to early recurrence. A 7-component panel was developed that had a negative predictive value of 83% and an accuracy of 78%. The accuracy was 70%.