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Journal and News Scan
The authors measured inlet and outlet orifice diameters and flow channel height of eight surgical bioprosthetic aortic stented valve models using an optical method. They demonstrated that in most valves (89 percent) the outlet orifice diameter is smaller than the inlet, resulting in a converging flow channel, while one model showed cylindrical geometry and another a diverging shape. Porcine valves exhibited higher gradient multipliers than bovine valves, with the Medtronic Avalus demonstrating the most favorable hemodynamic profile. The ratio between inlet and outlet diameters was consistent within each model type. The authors conclude that the outlet diameter is often the smallest and, therefore, hemodynamically most relevant dimension. They further emphasize that information on valve metrics is incomplete, scarce, and confusing, highlighting the need for more transparent and accessible reporting by manufacturers.
This single-center ambidirectional cohort study analyzed 617 patients with acute type A aortic dissection (ATAAD) who had coronary ostial involvement from 2019–2023. Patients underwent either isolated coronary ostial reconstruction (COR, n=507) or protective coronary artery bypass grafting (CABG, n=110), following COR or suture closure in severe cases (Neri A >50 percent margin, Neri B with distal entry, Neri C). Despite presenting with more severe coronary involvement and higher rates of malperfusion, the CABG group had significantly less procedural myocardial injury (2.7 percent vs 9.3 percent) and a trend toward fewer serious adverse events (2.7 percent vs 8.1 percent). Multivariable regression confirmed that protective CABG reduced serious adverse events (OR 0.24, P=0.028). The median follow-up was 26 months. Long-term survival did not differ between groups, although graft occlusion occurred in approximately 22 percent of CABG patients at two years. The authors conclude that protective CABG enhances perioperative safety in severe ATAAD coronary involvement without compromising long-term survival.
This article reviews lymph node dissection and its relationship to postoperative chylothorax in thoracic surgery. The authors analyze patterns of nodal involvement, technical considerations during mediastinal lymphadenectomy, and factors contributing to thoracic duct injury. They highlight that while comprehensive lymph node dissection is essential for accurate staging and potentially improved oncologic outcomes, it carries a measurable risk of chylothorax, particularly with extensive mediastinal nodal clearance. The paper emphasizes early recognition, standardized management strategies, and the importance of balancing oncological thoroughness with the risk of complications.
This work is significant because chylothorax remains a challenging and sometimes underreported complication in cardiothoracic surgery, associated with increased morbidity, prolonged hospitalization, and complex decision-making around reintervention. The paper provides both practical insights for surgical techniques and evidence-based strategies for managing complications, making it directly relevant to daily thoracic surgical practice and multidisciplinary perioperative care worldwide.
This article argues that emergency resternotomy should be routinely practiced in all cardiac surgery centers, as it is a critical procedure for managing cardiac arrest such as tamponade or refractory bleeding. The authors stress the importance of training and protocols to ensure quick and effective resternotomy, which can significantly improve patient outcomes compared to standard resuscitation methods, ultimately reducing the risk of neurological damage and mortality.
This single-center retrospective study compared the outcomes of mitral valve (MV) surgery vs transcatheter edge-to-edge repair (TEER) in octogenarians with moderate-to-severe or severe mitral regurgitation (MR). Between 2014 and 2024, 744 patients aged 80 years and older underwent MV intervention. After exclusions and 1:1 propensity matching, 252 patients (126 per group) were analyzed. Thirty-day mortality was low and similar between the groups (1.6 percent for surgery vs 0.8 percent for TEER). Surgery was associated with higher early morbidity (atrial fibrillation, prolonged ventilation, and longer ICU/hospital stays), but echocardiography at discharge showed less residual MR and tricuspid regurgitation, as well as lower right ventricular systolic pressure. At the median follow-up of 3.9-years, recurrent MR was significantly less frequent after surgery (6 percent vs 33 percent), and five-year survival favored surgery (68 percent vs 56 percent). While TEER offered advantages such as shorter hospitalization and fewer immediate complications, surgery provided superior valve durability, fewer reinterventions, reduced heart failure readmissions, and improved long-term survival in appropriately selected octogenarians.
This article reports the first pig-to-human lung xenotransplantation, marking a major milestone in thoracic transplantation research. A six-gene-edited porcine lung was transplanted into a 39-year-old brain-dead human recipient and monitored for 216 hours. The xenograft remained viable without evidence of hyperacute rejection or infection, demonstrating the feasibility of this approach. However, challenges emerged. Severe edema resembling primary graft dysfunction occurred within 24 hours, likely due to ischemia-reperfusion injury, and antibody-mediated rejection contributed to graft injury on postoperative days three and six, with partial recovery by day nine. The study employed an intensive multidrug immunosuppressive regimen tailored to the immune status throughout the monitoring period.
This case is highly significant for the CTSNet global cardiothoracic surgery audience, as it represents a proof-of-concept step toward lung xenotransplantation as a potential solution to donor shortages. While rejection and immunologic barriers remain formidable, these findings provide critical insights that will guide future preclinical and translational research.
This study reported favorable early outcomes in 11 intermediate- and high-risk patients who underwent a modified Bio-Bentall procedure with a rapid deployment valve between January 2018 and December 2022.
The technique involved inserting an inverted 8 cm Valsalva graft into the left ventricular outflow tract using a single-layer continuous suture anastomosis. The graft was then exteriorized, and the coronary buttons were reimplanted. Three simple interrupted anchoring sutures were placed and the valve was deployed.
The median patient age was 71 years, with the most common primary indication being annuloaortic ectasia with aortic insufficiency in six out of 11 patients. The median cardiopulmonary bypass and aortic cross-clamp times were 99 and 73 minutes, respectively. No early mortalities, reoperations, or paravalvular leaks were reported during follow-up. At one year, survival was 90.9 percent, and at three years, it was 54.5 percent. Permanent pacemaker implantation was required in three patients, with the authors attributing only one case to the rapid deployment technique.
The authors report the first Dutch experience with Personalized External Aortic Root Support (PEARS) in patients at risk of aortic dissection due to connective tissue disorders or bicuspid aortic valve. Between 2018 and 2023, 90 patients underwent surgery in Amsterdam and Leiden. Most were young adults, often with Marfan syndrome, Loeys-Dietz syndrome, or bicuspid valves. PEARS involves placing a tailor-made polyester mesh around the aortic root to prevent further enlargement while preserving the native valve. In this cohort, two-thirds had isolated PEARS, while others received it with a Ross procedure or other cardiac surgery. Short-term results were encouraging. Procedural success was high, aortic dimensions stabilized, and no deaths or dissections occurred during follow-up. A few patients required reoperation, mainly due to coronary artery issues. The authors conclude that PEARS appears safe and effective in the short term but emphasize the need for longer follow-up and larger studies.
This manuscript reports a pregnant patient who developed thrombosis of her mechanical pulmonary valve, necessitating re-replacement of the valve and the trunk.
A 30-year-old woman at 18 weeks of gestation presented with severe fatigue. Her medical history was significant for congenital pulmonary atresia with a ventricular septal defect, prior placement of a Blalock-Taussig shunt, multiple graft replacements, and a mechanical pulmonary valve replacement. The authors were concerned about prosthetic valve thrombosis after echocardiography, which was subsequently confirmed by cardiac MRI.
Given her pregnancy, conventional medical therapy was attempted first but proved unsuccessful; therefore, surgical intervention was deemed necessary.
The patient underwent re-replacement of the pulmonary valve and trunk using a pulmonary homograft. The procedure was performed on a beating heart, with cardiopulmonary bypass (CPB) initiated via a pulsatile roller pump. Her postoperative course was favorable, and she subsequently delivered a healthy infant at 38 weeks of gestation.
This case highlights that pulmonary valve re-replacement can be performed safely during pregnancy in the setting of mechanical valve thrombosis. The authors attribute the favorable outcome in part to the use of a beating-heart technique and optimized CPB parameters.
This narrative review examines the impact of depression on outcomes after cardiac surgery. The authors synthesized evidence from PubMed and Google Scholar, focusing on the epidemiology, mechanisms, and management of depression in this context. They report that preoperative depression is common, affecting up to 60 percent of patients, and is consistently linked to worse outcomes, including higher mortality, rehospitalizations, postoperative delirium, cognitive dysfunction, longer hospital stays, and reduced quality of life. Proposed mechanisms include inflammation, sympathetic overactivity, endothelial dysfunction, and platelet activation, compounded by adverse health behaviors and socioeconomic or psychosocial stressors. Women are diagnosed with depression more frequently, although male presentations may be underrecognized. The authors emphasize that depression is underdiagnosed in surgical practice, despite clear prognostic implications. They highlight evidence that the continuation of antidepressants, cognitive behavioral therapy, and structured exercise can improve outcomes. The review concludes that routine depression screening and the integration of psychological care into multidisciplinary perioperative pathways are essential.