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Journal and News Scan

Source: MMCTS
Author(s): Sahin Senay, Ahmet Umit Gullu, Muharrem Kocyigit, Aleks Degirmencioglu, Hasan Karabulut, and Cem Alhan. Multimed Man Cardiothorac Surg 2014 2014: mmu016


This study demonstrates the basic concepts and technique of robotic mitral valve replacement for valve pathologies that are not suitable for repair. Among this group of patients, robotic surgery is still feasible with some technical differences from a standard robotic mitral valve repair procedure.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Isabelle Opitz, Raphael Bueno, Eric Lim, Harvey Pass, Ugo Pastorino, Mattia Boeri, and Gaetano Rocco on behalf of the ESTS Biology Club

This paper presents an update on diagnostic and prognostic biomarkers in malignant pleural mesothelioma considering also recent molecular biologic achievements as microRNA and genomic sequencing.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Emma C. Hansson, Helena Rexius, Mikael Dellborg, Per Albertsson, and Anders Jeppsson

This prospective observational study compares patients with coronary artery bypass grafting on aspirin and ticagrelor (n = 173) or on aspirin and clopidogrel (n = 232). Major bleeding complications occurred in 14.5% with ticagrelor and 13.8% with clopidogrel (p=0.89). 

No significant differences were observed, too, when the drugs were discontinued ≥5  or 2-4 days before surgery. A strong tendency to more bleeding complications in the ticagrelor group was found, however, when the drugs were given until 0–1 day before surgery.



Source: European Journal of Cardio-Thoracic Surgery
Author(s): Catalin Constantin Badiu, Marcus André Deutsch, Constantinos Sideris, Markus Krane, Ina Hettich, Bernhard Voss, Domenico Mazzitelli, and Rüdiger Lange

The authors compare 3 groups of patients undergoing aortic root replacement for ascending aorta aneurysm: valve-sparing root replacement (VSRR, n = 178), Bentall procedure with biological conduit (n = 91) or mechanical conduit (n = 101). Patients with VSRR had the best 5-year survival and low incidence of bleeding complications. The authors suggest the VSRR procedure as first choice for patients with ascending aortic aneurysms.


Source: European Journal of Cardio-Thoracic Surgery
Author(s): Cora Lueders, Ben Jastram, Roland Hetzer, and Hartmut Schwandt

This exiting paper describes current achievements and open questions on the way to the manufacturing of heart valves using 3D printing.


Source: European Journal of Cardio-Thoracic Surgery
Author(s): Philippe Kolh, Stephan Windecker, Fernando Alfonso, Jean-Philippe Collet, Jochen Cremer, Volkmar Falk, et al.

Fifty years after the first coronary artery bypass grafting, the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) issued together guidelines for myocardial revascularization. In this document ESC and EACTS provide recommendations for revascularization of stable coronary artery disease, non-ST-segment elevation acute coronary syndrome, ST-segment elevation myocardial infarction and revascularization in patients with different risk factors. The authors underline the importance of interaction between cardiologists, cardiac surgeons and referring physicians for choosing the best possible revascularization approach.

Source: New England Journal of Medicine
Author(s): Jonathan Ailon, Ophyr Mourad, Vince Chien, Tomas Saun, and Shelly P. Dev

A well done video describing radial artery line placement aided by US.

Source: New England Journal of Medicine
Author(s): LB Holst and others for the TRISS Trial Group and the Scandinavian Critical Care Trials Group

This randomized trial investigated two different thresholds for triggering transfusion in patients with septic shock: 9 g/dL or 7 g/dL.  The lower threshold group received a median of 1 unit of blood compared to 4 in the higher threshold group.  90 day mortality rates and other morbidity were similar between the groups.  

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Hickey GL, Grant SW, Bridgewater B, Kendall S, Bryan AJ, Kuo J, Dunning J

This study utilised data form the UK National Adult Cardiac Surgery Audit to compare re-intervention free survival between porcine and bovine pericardial aortic valves. All elective or urgent aortic valve replacements with or without coronary artery surgery between 2003 and 2013 were included with a median follow-up time of 3.6 years. There was no difference in in-hospital mortality, survival (10-year survival of 49.0% and 50.3% in the bovine pericardial and porcine groups respectively) or re-intervention free survival between the groups. After adjustment there was a trend towards improved re-intervention free survival in younger patients (<60) who received porcine valves. 

Source: Annals of Surgery
Author(s): Gronnier, Caroline; Tréchot, Boris; Duhamel, Alain; Mabrut, Jean-Yves; Bail, Jean-Pierre; Carrere, Nicolas; Lefevre, Jérémie H.; Brigand, Cécile; Vaillant, Jean-Christophe; Adham, Mustapha; Msika, Simon; Demartines, Nicolas; El Nakadi, Issam; Piessen, Guillaume; Meunier, Bernard; Collet, Denis; Mariette, Christophe; On behalf of the FREGAT Working GroupFRENCHAFC

This multicenter prospective trial evaluated the impact of induction therapy on anastomotic leak (AL) and other complications after esophagectomy.  Of 2944 included pts, 593 had induction chemoradiotherapy.  AL occurred in 8.8% of induction therapy pts compared to 10.6% of surgery only patients.  90 day postoperative morbidity and mortality rates were similar between the groups. Chylothorax, cardiovascular complications, and VTE events were more common after induction therapy.